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安全信息

I1149

Sigma-Aldrich

碘乙酰胺

BioUltra

别名:

2-Iodoacetamide, Monoiodoacetamide, alpha-Iodoacetamide

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10 G
¥2,708.30
50 G
¥9,027.55

¥2,708.30


预计发货时间2025年7月07日详情


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10 G
¥2,708.30
50 G
¥9,027.55

About This Item

线性分子式:
ICH2CONH2
CAS Number:
分子量:
184.96
Beilstein:
1739080
EC 号:
MDL编号:
UNSPSC代码:
12352202
PubChem化学物质编号:
NACRES:
NA.77

¥2,708.30


预计发货时间2025年7月07日详情


获取大包装报价

生物来源

synthetic (organic)

质量水平

产品线

BioUltra

方案

≥99% (NMR)

表单

powder

杂质

≤0.0005% Phosphorus (P)
≤0.1% Insoluble matter

mp

92-95 °C (lit.)

溶解性

H2O: 0.5 M, clear, colorless

痕量阴离子

chloride (Cl-): ≤0.05%
sulfate (SO42-): ≤0.05%

痕量阳离子

Al: ≤0.0005%
Ca: ≤0.0005%
Cu: ≤0.0005%
Fe: ≤0.0005%
K: ≤0.005%
Mg: ≤0.0005%
NH4+: ≤0.05%
Na: ≤0.05%
Pb: ≤0.001%
Zn: ≤0.0005%

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此商品
333530339830318345
assay

98%

assay

90%

assay

99%

assay

97%

Quality Level

100

Quality Level

100

Quality Level

100

Quality Level

100

density

0.719 g/mL at 25 °C (lit.)

density

1.121 g/mL at 25 °C (lit.)

density

0.877 g/mL at 25 °C (lit.)

density

0.899 g/mL at 25 °C (lit.)

refractive index

n20/D 1.407 (lit.)

refractive index

n20/D 1.462 (lit.)

refractive index

n20/D 1.440 (lit.)

refractive index

n20/D 1.453 (lit.)

bp

84-88 °C (lit.)

bp

82-85 °C/60 mmHg (lit.)

bp

95 °C/7 mmHg (lit.)

bp

162-163 °C/768 mmHg (lit.)

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

-

storage temp.

2-8°C

应用

碘乙酰胺已用于:
  • 蛋白质组学分析的蛋白质消化
  • 烷基化蛋白质样品
  • 牛奶过敏原、β-乳球蛋白(BLG)和α-乳清蛋白(ALA)的变性

生化/生理作用

碘乙酰胺在肽测序中胱氨酸残基的烷基化试剂。它是活性位点上含有胱氨酸的酶的的一种不可逆抑制剂。它与组氨酸残基的反应速度要慢得多,但这种活性是核糖核酸酶抑制的原因。
碘乙酰胺(IAA)被用于抑制糖酵解,因为它能够不可逆地抑制糖酵解酶甘油醛-3-磷酸脱氢酶(GAPDH)。IAA用于研究半胱氨酸残基在酶催化和脑细胞转运过程中的作用。它可以与巯基乙醇和谷胱甘肽等低分子量硫醇化合物发生反应。IAN还可能阻断菠萝蛋白酶、组织蛋白酶C、梭状芽孢蛋白酶和羧肽酶P等酶。

象形图

Skull and crossbonesHealth hazard

警示用语:

Danger

危险分类

Acute Tox. 3 Oral - Aquatic Chronic 4 - Resp. Sens. 1 - Skin Sens. 1

储存分类代码

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges

法规信息

危险化学品
  • 技术规格说明书

  • 历史批次信息供参考:

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