I134
L-N5-（1-氨基乙基）鸟氨酸 盐酸盐
≥95% (HPLC)
别名:
L-NIO hydrochloride, L-Ornithine ψ-acetamidine hydrochloride
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关于此项目
经验公式（希尔记法）:
C7H15N3O2 · xHCl
化学文摘社编号:
分子量:
173.21 (free base basis)
NACRES:
NA.26
PubChem Substance ID:
UNSPSC Code:
12352204
MDL number:
Form:
powder
Assay:
≥95% (HPLC)
Mol wt:
calculated mol wt 173.22 g/mol
InChI key
JIBZSGQTCBWUKL-RGMNGODLSA-N
SMILES string
CC(NCCC[C@H](N)C(O)=O)=N.[H]Cl
InChI
1S/C7H15N3O2.ClH/c1-5(8)10-4-2-3-6(9)7(11)12;/h6H,2-4,9H2,1H3,(H2,8,10)(H,11,12);1H/t6-;/m0./s1
assay
≥95% (HPLC)
form
powder
mol wt
calculated mol wt 173.22 g/mol
storage condition
desiccated, under inert gas
color
white to beige
solubility
H2O: 2 mg/mL, clear (warmed)
storage temp.
−20°C
Quality Level
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相关类别
Application
L-N5-(1-Iminoethyl) ornithine hydrochloride has been used to study the effects of the cytotoxic drug paclitaxel and carbachol (a cholinergic agonist) to induce death in breast tumor MCF-7 cells and the role of nitric oxide synthase (NOS) in this effect. It has also been used to study its effects on pulmonary arterial responses to sufentanil in the feline pulmonary vascular bed.
Biochem/physiol Actions
A potent irreversible inhibitor of nitric oxide synthase.
存储类别
11 - Combustible Solids
wgk
WGK 3
ppe
dust mask type N95 (US), Eyeshields, Gloves
法规信息
新产品
此项目有
International Review of Neurobiology, 42 (1998)
The effects of sufentanil in the feline pulmonary vascular bed
Alan D Kaye
European Journal of Pharmacology (2006)
Participation of non-neuronal muscarinic receptors in the effect of carbachol with paclitaxel on human breast adenocarcinoma cells. Roles of nitric oxide synthase and arginase
Alejandro Javier Espa?ol
International Immunopharmacology, 29(1) (2015)
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