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Merck
CN

I134

L-N5-(1-氨基乙基)鸟氨酸 盐酸盐

≥95% (HPLC)

别名:

L-NIO hydrochloride, L-Ornithine ψ-acetamidine hydrochloride

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关于此项目

经验公式(希尔记法):
C7H15N3O2 · xHCl
化学文摘社编号:
分子量:
173.21 (free base basis)
NACRES:
NA.26
PubChem Substance ID:
UNSPSC Code:
12352204
MDL number:
Form:
powder
Assay:
≥95% (HPLC)
Mol wt:
calculated mol wt 173.22 g/mol
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Quality Segment

assay

≥95% (HPLC)

form

powder

mol wt

calculated mol wt 173.22 g/mol

storage condition

desiccated, under inert gas

color

white to beige

solubility

H2O: 2 mg/mL, clear (warmed)

storage temp.

−20°C

SMILES string

CC(NCCC[C@H](N)C(O)=O)=N.[H]Cl

InChI

1S/C7H15N3O2.ClH/c1-5(8)10-4-2-3-6(9)7(11)12;/h6H,2-4,9H2,1H3,(H2,8,10)(H,11,12);1H/t6-;/m0./s1

InChI key

JIBZSGQTCBWUKL-RGMNGODLSA-N

Application

L-N5-(1-Iminoethyl) ornithine hydrochloride has been used to study the effects of the cytotoxic drug paclitaxel and carbachol (a cholinergic agonist) to induce death in breast tumor MCF-7 cells and the role of nitric oxide synthase (NOS) in this effect. It has also been used to study its effects on pulmonary arterial responses to sufentanil in the feline pulmonary vascular bed.

Biochem/physiol Actions

A potent irreversible inhibitor of nitric oxide synthase.


存储类别

11 - Combustible Solids

wgk

WGK 3

ppe

dust mask type N95 (US), Eyeshields, Gloves



历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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