I148
Imperatoxin A
>88%, lyophilized powder
别名:
Ip Txa
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关于此项目
经验公式（希尔记法）:
C148H260N58O45S6
化学文摘社编号:
分子量:
3764.40
UNSPSC Code:
12352200
NACRES:
NA.77
MDL number:
Biochem/physiol Actions
Selective skeletal-type ryanodine sensitive intracellular Ca2+ channel activator found in the scorpion Pandinus
Selective skeletal-type ryanodine sensitive intracellular Ca2+ channel activator.
Features and Benefits
This compound is featured on the InsP3/Ryanodine Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
存储类别
13 - Non Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
法规信息
新产品
此项目有
F Z Zamudio et al.
FEBS letters, 405(3), 385-389 (1997-04-01)
We present the complete amino acid sequence of Imperatoxin A (IpTx(a)), a 33-amino-acid peptide from the venom of the scorpion P. imperator which activates Ca2+ release channels/ryanodine receptors (RyR) of sarcoplasmic reticulum (SR). The amino acid sequence of IpTx(a) shows
H H Valdivia et al.
Proceedings of the National Academy of Sciences of the United States of America, 89(24), 12185-12189 (1992-12-15)
We report the purification of two peptides, called "imperatoxin inhibitor" and "imperatoxin activator," from the venom of the scorpion Pandinus imperator targeted against ryanodine receptor Ca(2+)-release channels. Imperatoxin inhibitor has a M(r) of approximately 10,500, inhibits [3H]ryanodine binding to skeletal
R el-Hayek et al.
The Journal of biological chemistry, 270(48), 28696-28704 (1995-12-01)
We have used [3H]ryanodine binding experiments and single channel recordings to provide convergent descriptions of the effect of imperatoxin A (IpTxa), a approximately 5-kDa peptide from the venom of the scorpion Pandinus imperator (Valdivia, H. H., Kirby, M. S., Lederer