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经验公式(希尔记法):
C11H9NO2
化学文摘社编号:
分子量:
187.19
UNSPSC Code:
12352106
NACRES:
NA.52
PubChem Substance ID:
EC Number:
214-872-7
Beilstein/REAXYS Number:
6317
MDL number:
产品名称
3-吲哚丙烯酸, powder
InChI key
PLVPPLCLBIEYEA-AATRIKPKSA-N
InChI
1S/C11H9NO2/c13-11(14)6-5-8-7-12-10-4-2-1-3-9(8)10/h1-7,12H,(H,13,14)/b6-5+
SMILES string
OC(=O)\C=C\c1c[nH]c2ccccc12
grade
Molecular Biology
assay
≥98.0% (HPLC)
≥98.0% (TLC)
form
powder
mol wt
187.19 g/mol
storage temp.
room temp
Quality Level
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Application
适用于诱导trpE启动子控制系统的基因转录。
Biochem/physiol Actions
3-吲哚丙烯酸有助于阻止粗糙脉孢菌(Neurospora crassa)的菌丝生长,导致细胞积累磷酸吲哚甘油,进而影响色氨酸合成酶的速率。
General description
3-吲哚丙烯酸(IAA)是一种用于诱导基因转录的化学物质。该表达系统要求将目的基因克隆到含有trpE启动子的质粒中。
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
Inhibition of tryptophan synthetase by indoleacrylic acid
Matchett W H
Journal of Bacteriology, 110(1), 146-154 (1972)
D N Wilson et al.
RNA (New York, N.Y.), 6(12), 1704-1713 (2001-01-06)
Replacing a cassette of 31 residues from Escherichia coli release factor 1 with the equivalent residues in release factor 2 gave a protein active in codon-specific binding to the ribosome but inactive in peptidyl-tRNA hydrolysis. Such a phenotype is also
Indeok Hwang et al.
Plant molecular biology, 73(6), 629-641 (2010-05-18)
Shoot branching and growth are controlled by phytohormones such as auxin and other components in Arabidopsis. We identified a mutant (igi1) showing decreased height and bunchy branching patterns. The phenotypes reverted to the wild type in response to RNA interference
J K Johnson et al.
Biochemistry, 33(15), 4738-4744 (1994-04-19)
In a previous paper, we demonstrated that the medium-chain fatty acyl-CoA dehydrogenase-catalyzed (MCAD-catalyzed) reductive half-reaction of indolepropionyl-CoA proceeds via formation of a chromophoric intermediary species "X" (absorption maximum = 400 nm) and proposed that the decay of this species might
E Marklová
Amino acids, 17(4), 401-413 (2000-03-09)
In addition to the main catabolic routes of tryptophan (Trp), there exist minor and less thoroughly investigated pathways; one of these leads to indolylacrylic acid (IAcrA). IAcrA is a plant growth hormone, whereas its biological role in animals is still
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