I1637
Ipratropium bromide monohydrate
≥98% (TLC), powder
别名:
Atropine isopropyl bromide
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关于此项目
经验公式（希尔记法）:
C20H30BrNO3 · H2O
化学文摘社编号:
分子量:
430.38
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352200
EC Number:
244-873-8
MDL number:
Assay:
≥98% (TLC)
Form:
powder
Quality Segment
assay
≥98% (TLC)
form
powder
color
white
solubility
H2O: 10 mg/mL
originator
Boehringer Ingelheim
SMILES string
O.[Br-].CC(C)[N@+]1(C)[C@H]2CC[C@@H]1C[C@@H](C2)OC(=O)C(CO)c3ccccc3
InChI
1S/C20H30NO3.BrH.H2O/c1-14(2)21(3)16-9-10-17(21)12-18(11-16)24-20(23)19(13-22)15-7-5-4-6-8-15;;/h4-8,14,16-19,22H,9-13H2,1-3H3;1H;1H2/q+1;;/p-1/t16-,17+,18+,19?,21?;;
InChI key
KEWHKYJURDBRMN-XSAPEOHZSA-M
Gene Information
human ... CHRM1(1128), CHRM2(1129), CHRM3(1131), CHRM4(1132), CHRM5(1133)
Application
Ipratropium bromide monohydrate has been used for the inhibition of peripheral muscarinic receptors in rats.
Biochem/physiol Actions
Ipratropium bromide monohydrate is a nonselective muscarinic acetylcholine receptor antagonist and a bronchodilator. In nebulized form, it is used for treating asthma and obstructive pulmonary diseases. It acts as a β2 adrenoreceptor agonist. Ipratropium bromide monohydrate is an anticholinergic agent and competes with acetylcholine. It promotes bronchodilation by stimulating sympathetic pathways.
Features and Benefits
This compound was developed by Boehringer Ingelheim. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.
Other Notes
N-isopropyl quaternary salt of atropine.
signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2
存储类别
11 - Combustible Solids
wgk
WGK 2