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Merck
CN

I1774

Sigma-Aldrich

伊枯草菌素A 来源于枯草芽孢杆菌

≥95% (HPLC), suitable for microbiological culture

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产品名称

伊枯草菌素A 来源于枯草芽孢杆菌, ≥95% (HPLC)

生物来源

Bacillus subtilis

质量水平

方案

≥95% (HPLC)

表单

powder

技术

microbiological culture: suitable

颜色

white to yellow

溶解性

ethanol: soluble 9.80-10.20 mg/mL

抗生素抗菌谱

fungi

作用机制

cell membrane | interferes

储存温度

2-8°C

应用

伊枯草菌素A 用于 Bacillomycin D(一种具有抗黄曲霉抗真菌活性的 伊枯草菌素)的研究

生化/生理作用

伊枯草菌素A 对致病性酵母和真菌有很强的抗真菌活性。它与靶细胞的细胞质膜相互作用,形成离子传导孔。其作用方式可归因于其与固醇和磷脂的相互作用。该化合物导致人红细胞释放外囊泡(exo-vesicle)。

其他说明

一个脂肽家族,其特征在于以C13-C17 β氨基脂肪酸环化的七肽。主要由C14-C15 β氨基酸组成。

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)

法规信息

涉药品监管产品
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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Dehui Yao et al.
World journal of microbiology & biotechnology, 28(3), 985-991 (2012-07-19)
The strain 3-10 was isolated from soil and identified as B. subtilis according to morphological and physiological characteristics and nucleotide sequence of 16S rRNA. It co-produced anti-fungal iturin A and fertilizer synergist of poly-γ-glutamic acid (γ-PGA) under solid state fermentation
E Jourdan et al.
Molecular plant-microbe interactions : MPMI, 22(4), 456-468 (2009-03-11)
Multiple strains of Bacillus subtilis were demonstrated to stimulate plant defense responses, and cyclic lipopeptides may be involved in the elicitation of this induced systemic resistance phenomenon. Here, we further investigated molecular events underlying the interaction between such lipopeptides and
Chie Niisawa et al.
The Journal of general and applied microbiology, 54(3), 149-158 (2008-07-26)
A composting product of marine animal resources has been used as a fertilizer and a soil conditioner in Japan. This compost was produced by a repeated fed-batch fermentation system with three successive aerobic bioreactors. Composting temperature reached about 75 degrees
Jun Yuan et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 879(26), 2746-2750 (2011-08-30)
Iturin A, a powerful antifungal surfactant, is a kind of bacterial lipopeptide produced by Bacillus strains. This study addresses the use of an aqueous two-phase system (ATPS) using ethanol/ammonium sulfate to extract iturin A from Bacillus amyloliquefaciens NJN-6 fermentation broth
Minakshi Grover et al.
Current microbiology, 60(2), 99-106 (2009-09-25)
Bacillus subtilis strain RP24, isolated from rhizoplane of field grown pigeon pea, exhibited in vitro antagonism against a wide range of phytopathogenic fungi. An attempt was made to partially purify and characterize the diffusible antifungal metabolite/s produced by the strain

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