biological source
mouse
Quality Segment
recombinant
expressed in E. coli
assay
≥97% (SDS-PAGE)
form
lyophilized powder
potency
1-10 ng/mL EC50
mol wt
11.5 kDa (predicted; 9 kDa under reducing conditions)
packaging
pkg of 5 μg
technique(s)
cell culture | mammalian: suitable
impurities
endotoxin, tested
UniProt accession no.
storage temp.
−20°C
Gene Information
mouse ... Il13(16163)
Biochem/physiol Actions
白细胞介素-13是由小鼠和人类中活化的Th2细胞产生的多效性细胞因子。IL-13主要分泌为132个氨基酸的未糖基化蛋白,分子量为10,000道尔顿。对小鼠IL-13基因的4.3 kb DNA片段进行测序,并以映射11号染色体的单拷贝形式出现。在人类中,IL-13基因的4.6 kb DNA片段以单拷贝形式出现,并映射到5号染色体。IL-13诱导B细胞增殖,还诱导IgE转换。使用人红白血病细胞系TF-1在培养物中检测人和小鼠IL-13产品的增殖活性。
Physical form
从含有50 μg牛血清白蛋白(BSA)/1 μg细胞因子的磷酸盐缓冲盐水(PBS)(pH值7.4)的0.2 μm过滤溶液中冻干
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves