I2273
3-吲哚丙烯酸
BioReagent, ≥98% (HPLC)
别名:
3-（3-吲哚基）丙烯酸, IAA
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关于此项目
经验公式（希尔记法）:
C11H9NO2
化学文摘社编号:
分子量:
187.19
UNSPSC Code:
12352106
NACRES:
NA.52
PubChem Substance ID:
EC Number:
214-872-7
Beilstein/REAXYS Number:
6317
MDL number:
产品名称
3-吲哚丙烯酸, BioReagent, ≥98% (HPLC)
InChI key
PLVPPLCLBIEYEA-AATRIKPKSA-N
InChI
1S/C11H9NO2/c13-11(14)6-5-8-7-12-10-4-2-1-3-9(8)10/h1-7,12H,(H,13,14)/b6-5+
SMILES string
OC(=O)\C=C\c1c[nH]c2ccccc12
grade
Molecular Biology
product line
BioReagent
assay
≥98% (HPLC)
form
powder
mol wt
187.19 g/mol
storage temp.
room temp
Quality Level
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General description
3-吲哚丙烯酸（IAA）是一种用于诱导基因转录的化学物质。该表达系统要求将目的基因克隆到含有 trpE 启动子的质粒中。
Application
3-吲哚丙烯酸已被用于在大肠杆菌中诱导核糖激酶的表达。
Biochem/physiol Actions
3-吲哚丙烯酸 (IAA) 由色氨酸代谢，这种转化通过肠道菌群进行。3-吲哚丙烯酸 (IAA) 是一种用于诱导基因转录的化学物质。IAA 诱导表达系统需要将目标基因克隆到含有色氨酸启动子的质粒中。它能促进肠上皮细胞的屏障功能。IAA 也有利于抗炎反应，并被视为炎症性肠病 (IBD) 的潜在治疗方法。它还参与多种细胞过程，包括凋亡、自噬、细胞增殖和迁移。另据报道，在肿瘤细胞中，IAA 可阻碍色氨酸代谢。
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
signalword
Warning
hcodes
target_organs
Respiratory system
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
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