Merck
CN

I2512

Sigma-Aldrich

碘乙酸钠

≥98%

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别名:
碘乙酸 钠盐
线性分子式:
ICH2COONa
CAS号:
分子量:
207.93
Beilstein:
4009322
EC 号:
MDL编号:
PubChem化学物质编号:
NACRES:
NA.77

生物来源

synthetic (organic)

质量水平

检测方案

≥98%

形式

powder

mp

208 °C (dec.) (lit.)

溶解性

H2O: 100 mg/mL

储存温度

−20°C

SMILES字符串

[Na+].[O-]C(=O)CI

InChI

1S/C2H3IO2.Na/c3-1-2(4)5;/h1H2,(H,4,5);/q;+1/p-1

InChI key

AGDSCTQQXMDDCV-UHFFFAOYSA-M

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应用

用于修饰蛋白质中半胱氨酸残基的试剂。用于蛋白质测序(包括 Sanger 测序牛胰岛素)以防止 -SH 侧链的氧化。
用于修饰蛋白质中半胱氨酸残基的试剂。用于诱导动物骨关节炎模型系统,其模拟人类疾病的症状和组织病理学。

生化/生理作用

用于诱导大鼠骨关节炎样病变和功能障碍,用于测试软骨保护剂和诊断成像技术。

象形图

CorrosionSkull and crossbones

警示用语:

Danger

危险声明

危险分类

Acute Tox. 3 Oral - Eye Dam. 1 - Skin Corr. 1B

储存分类代码

6.1A - Combustible, acute toxic Cat. 1 and 2 / very toxic hazardous materials

WGK

WGK 3

闪点(°F)

406.4 °F

闪点(°C)

208 °C

个人防护装备

Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges


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Matilde Tschon et al.
Cells, 9(7) (2020-07-02)
The purpose of this study was to verify the efficacy of a single intra-articular (i.a.) injection of a hyaluronic acid-chitlac (HY-CTL) enriched with two low dosages of triamcinolone acetonide (TA, 2.0 mg/mL and 4.5 mg/mL), in comparison with HY-CTL alone
Ikufumi Takahashi et al.
PloS one, 13(4), e0196625-e0196625 (2018-04-27)
This study aimed to investigate the histopathological changes in the patellofemoral joint using a rat model of osteoarthritis that was induced using monosodium iodoacetate, and to establish a novel model of patellofemoral osteoarthritis in a rat model using histopathological analysis.
Kuo-Ti Peng et al.
Clinical science (London, England : 1979), 133(21), 2171-2187 (2019-11-07)
Several diseases have been linked to particulate matter (PM) exposure. Outdoor activities, such as road running or jogging, are popular aerobic exercises due to few participatory limitations. Osteoarthritis (OA) is a progressive degenerative joint disease, usually observed at age 40
S E Bove et al.
Osteoarthritis and cartilage, 11(11), 821-830 (2003-11-12)
To describe an in vivo model in the rat in which change in weight distribution is used as a measure of disease progression and efficacy of acetaminophen and two nonsteroidal anti-inflammatory drugs (NSAIDs) in a model of monosodium iodoacetate (MIA)-induced
Hyung Jin Lim et al.
Food science & nutrition, 8(12), 6550-6556 (2020-12-15)
In Asia, Vigna angularis (azuki bean) has been used as a traditional medicine to treat various diseases because of its biological properties. Osteoarthritis (OA) and osteoporosis (OP) are common regenerative bone diseases that are characterized by deterioration of joint and

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