I2512
碘乙酸钠
powder, ≥98%
别名:
碘乙酸 钠盐
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关于此项目
线性分子式:
ICH2COONa
化学文摘社编号:
分子量:
207.93
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352202
EC Number:
206-165-7
MDL number:
Beilstein/REAXYS Number:
4009322
Application
用于修饰蛋白质中半胱氨酸残基的试剂。
用于修饰蛋白质中半胱氨酸残基的试剂。用于蛋白质测序（包括 Sanger 测序牛胰岛素）以防止 -SH 侧链的氧化。
用于修饰蛋白质中半胱氨酸残基的试剂。用于诱导动物骨关节炎模型系统，其模拟人类疾病的症状和组织病理学。
Biochem/physiol Actions
用于诱导大鼠骨关节炎样病变和功能障碍，用于测试软骨保护剂和诊断成像技术。
signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 3 Oral - Eye Dam. 1 - Skin Corr. 1B
存储类别
6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
wgk
WGK 3
flash_point_f
406.4 °F
flash_point_c
208 °C
ppe
Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges
Roberto E Guzman et al.
Toxicologic pathology, 31(6), 619-624 (2003-10-31)
Osteoarthritis (OA) is a degenerative joint disease characterized by joint pain and a progressive loss of articular cartilage. Studies to elucidate the pathophysiology of OA have been hampered by the lack of a rapid, reproducible animal model that mimics both
C Guingamp et al.
Arthritis and rheumatism, 40(9), 1670-1679 (1997-10-27)
To characterize the dose-responsiveness of morphologic and biochemical chondral changes relative to mobility in mono-iodoacetate (MIA)-induced osteoarthritis (OA) in rats. Rat mobility was assessed by biotelemetry. Articular lesions were characterized by macroscopic and histologic examinations. Cartilage proteoglycan metabolism was evaluated
Hyung Jin Lim et al.
Food science & nutrition, 8(12), 6550-6556 (2020-12-15)
In Asia, Vigna angularis (azuki bean) has been used as a traditional medicine to treat various diseases because of its biological properties. Osteoarthritis (OA) and osteoporosis (OP) are common regenerative bone diseases that are characterized by deterioration of joint and
Matilde Tschon et al.
Cells, 9(7) (2020-07-02)
The purpose of this study was to verify the efficacy of a single intra-articular (i.a.) injection of a hyaluronic acid-chitlac (HY-CTL) enriched with two low dosages of triamcinolone acetonide (TA, 2.0 mg/mL and 4.5 mg/mL), in comparison with HY-CTL alone
Ikufumi Takahashi et al.
PloS one, 13(4), e0196625-e0196625 (2018-04-27)
This study aimed to investigate the histopathological changes in the patellofemoral joint using a rat model of osteoarthritis that was induced using monosodium iodoacetate, and to establish a novel model of patellofemoral osteoarthritis in a rat model using histopathological analysis.
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