I2760
(-)-异丙肾上腺素 (+)-酒石酸氢盐
β-adrenoceptor agonist, powder
别名:
(-)-异丙去甲肾上腺素 (+)-酒石酸氢盐
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关于此项目
经验公式（希尔记法）:
C11H17NO3 · C4H6O6
化学文摘社编号:
分子量:
361.34
UNSPSC Code:
51111800
PubChem Substance ID:
NACRES:
NA.77
MDL number:
Form:
powder
Quality level:
产品名称
(-)-异丙肾上腺素 (+)-酒石酸氢盐, powder
form
powder
Quality Level
color
white to off-white
solubility
H2O: ≥50 mg/mL, clear, colorless to faintly yellow
originator
Sanofi Aventis
SMILES string
O[C@@H]([C@H](O)C(O)=O)C(O)=O.CC(C)NC[C@H](O)c1ccc(O)c(O)c1
InChI
1S/C11H17NO3.C4H6O6/c1-7(2)12-6-11(15)8-3-4-9(13)10(14)5-8;5-1(3(7)8)2(6)4(9)10/h3-5,7,11-15H,6H2,1-2H3;1-2,5-6H,(H,7,8)(H,9,10)/t11-;1-,2-/m00/s1
InChI key
LBOPECYONBDFEM-RWALOXMOSA-N
Gene Information
human ... ADRB1(153), ADRB2(154), ADRB3(155)
Application
(−)-Isoproterenol (+)-bitartrate salt has been used:
- as a component in KRH medium for cyclic adenosine monophosphate (cAMP) assay
- to stimulate preadipocytes to study its concentration responsive curve
- to intraperitoneally administer to mice to evaluate whether the multi-dry-electrode plate (MDEP)-sensor system can assess drug responses
Biochem/physiol Actions
Isoproterenol functions as an ovine pulmonary vein dilator.
β-肾上腺素受体激动剂；增加细胞溶质 cAMP。
Features and Benefits
This compound was developed by Sanofi Aventis. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
存储类别
11 - Combustible Solids
wgk
WGK 3
法规信息
新产品
此项目有
J M Bernstein et al.
The Journal of allergy and clinical immunology, 99(2), 165-175 (1997-02-01)
Nasal polyps and turbinates were obtained from individuals undergoing surgery for symptomatic nasal obstruction caused by nonatopic rhinosinusitis or allergic rhinosinusitis. One part of the tissue from each patient was fixed in neutral buffered formalin and prepared for study by
Jennifer N Gelinas et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 25(13), 3294-3303 (2005-04-01)
Long-term potentiation (LTP) is activity-dependent enhancement of synaptic strength that can critically regulate long-term memory storage. Like memory, LTP exhibits at least two mechanistically distinct temporal phases. Early LTP (E-LTP) does not require protein synthesis, whereas the late phase of
G C Rolband et al.
Journal of gerontology, 45(5), B174-B178 (1990-09-01)
The age-related declines in the antilipolytic and lipogenic actions of insulin were studied in adipocytes from rats aged 2, 6, 12, and 24 months. Since adenosine modulates insulin action, its concentration was controlled by treatment of adipocytes with adenosine deaminase
A Hartzshtark et al.
Experientia, 41(3), 378-379 (1985-03-15)
Local, externally applied pharmacological agents which are assumed to raise the c-AMP level, decrease the low pressure indentation value of the forehead skin of certain human volunteers.
V N Gurin et al.
Biulleten' eksperimental'noi biologii i meditsiny, 91(3), 304-305 (1981-03-01)
It was established in experiments on unanesthetized rats given intraventricular injections of drugs that hyperthermic effect of prostaglandin E2 (PGE2) was markedly weakened by administering clofelin while isoproterenol had no appreciable effect on PGE2 effects were not prevented by noradrenaline
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| I2760-1G | 04061833848623 |
| I2760-100MG | 04061833848616 |
| I2760-500MG | 04061833848630 |
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