I3766
异甘草素
powder
别名:
(E)-1-(2,4-二羟基苯基)-3-(4-羟基苯基)-2-丙烯-1-酮, 4,2′,4′-三羟基查尔酮
登录查看公司和协议定价
选择尺寸
关于此项目
经验公式(希尔记法):
C15H12O4
化学文摘社编号:
分子量:
256.25
Beilstein:
1914296
MDL编号:
UNSPSC代码:
41106305
PubChem化学物质编号:
NACRES:
NA.77
表单
powder
质量水平
颜色
yellow to orange
溶解性
H2O: <0.1 mg/mL
methanol: 10 mg/mL
DMSO: 20 mg/mL
储存温度
2-8°C
SMILES字符串
Oc1ccc(cc1)\C=C\C(=O)c2ccc(O)cc2O
InChI
1S/C15H12O4/c16-11-4-1-10(2-5-11)3-8-14(18)13-7-6-12(17)9-15(13)19/h1-9,16-17,19H/b8-3+
InChI key
DXDRHHKMWQZJHT-FPYGCLRLSA-N
基因信息
rat ... Alox5(25290)
正在寻找类似产品? 访问 产品对比指南
一般描述
异甘草素是一种芳香族酮,属于查耳酮化合物类。它来源于甘草,是药品和食品中的一种成分。
应用
异甘草素已被用于:
- 作为斑马鱼胚胎中的骨形态发生蛋白(BMP)激动剂
- 作为斑马鱼胚胎中的鸟苷酸环化酶激活剂
- 用于测试其对Epstein-Barr病毒相关胃癌的抗肿瘤和抗病毒作用
生化/生理作用
异甘草素是一种可溶性鸟苷酸环化酶激活剂,具有抗肿瘤活性。它还具有抗氧化、抗血小板和雌激素特性。
特点和优势
这种化合物是环核苷酸研究的特色产品。点击此处发现更多特色环核苷酸产品。在sigma.com/discover-bsm可了解更多关于生物活性小分子的其他研究领域。
免责声明
光敏性、吸湿性
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
Vasorelaxant effect of isoliquiritigenin, a novel soluble guanylate cyclase activator, in rat aorta.
S M Yu et al.
British journal of pharmacology, 114(8), 1587-1594 (1995-04-01)
1. The vasorelaxant activity of isoliquiritigenin, isolated from Dalbergia odorifera T, was investigated in the phenylephrine-precontracted rat aorta by measuring tension, guanylate and adenylate cyclase activities, guanosine 3':5'-cyclic monophosphate (cyclic GMP) and adenosine 3':5'-cyclic monophosphate (cyclic AMP) levels. 2. Isoliquiritigenin
Small molecule modifier screen for kit-dependent functions in zebrafish embryonic melanocytes
Hultman KA, et al.
Zebrafish, 5(4), 279-287 (2008)
Suengmok Cho et al.
Biochemical and biophysical research communications, 413(4), 637-642 (2011-09-29)
Isoliquiritigenin (ILTG) is a chalcone compound and has valuable pharmacological properties such as antioxidant, anti-inflammatory, anticancer, and antiallergic activities. Recently, the anxiolytic effect of ILTG has been reported; however, its action mechanism and hypnotic activity have not yet been demonstrated.
Xuan Yuan et al.
Recent patents on anti-cancer drug discovery, 8(2), 191-199 (2012-09-12)
Isoliquiritigenin (ISL), a licorice chalconoid, is a bioactive agent with chemopreventive potential that has been patented for tumor treatment in China. This study investigated the mechanisms of ISL-induced apoptosis in ovarian carcinoma SKOV-3 cells. Cell viability was evaluated using a
Wdr68 mediates dorsal and ventral patterning events for craniofacial development
Alvarado E, et al.
PLoS ONE, 11(11), e0166984-e0166984 (2016)
商品
Cyclic nucleotides like cAMP modulate cell function via PKA activation and ion channels.
我们的科学家团队拥有各种研究领域经验,包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系客户支持