I4028
Monoclonal Anti-Interleukin-18 Receptor antibody produced in mouse
clone 70625.111, purified immunoglobulin, lyophilized powder
别名:
Anti-IL-18 Receptor
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关于此项目
Conjugate:
unconjugated
Clone:
70625.111, monoclonal
Application:
FACS, ICC, IHC
Citations:
2
biological source
mouse
Quality Segment
conjugate
unconjugated
antibody form
purified immunoglobulin
antibody product type
primary antibodies
clone
70625.111, monoclonal
form
lyophilized powder
species reactivity
human
technique(s)
flow cytometry: suitable (2.5μg/SUP>106 cell), immunocytochemistry: 8-25 μg/mL, immunohistochemistry: 8-25 μg/mL
isotype
IgG1
UniProt accession no.
storage temp.
−20°C
target post-translational modification
unmodified
Gene Information
human ... IL18R1(8809)
General description
The antibody will neutralize the biological activity of recombinant human IL-18 receptor.
Immunogen
recombinant human IL-18 receptor extracellular domain, expressed in NS0 cells.
Biochem/physiol Actions
IL-18 belongs to the IL-1 cytokine superfamily and is a regulator of innate and acquired immune responses. The immune responses of IL-18 are mediated by its interaction and subsequent signaling by IL-18 receptor complex. The IL-18R complex is made up of α chain that binds to extracellular IL-18 and a β chain that is involved in signal transduction. The IL-18/IL-18R signaling enhances T and NK cell maturation, cytotoxicity and secretion of cytokines.
Physical form
Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline with 5% trehalose.
Preparation Note
Purified using protein G.
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存储类别
13 - Non Combustible Solids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable