I4144
IL-3 mouse
≥98% (SDS-PAGE), recombinant, expressed in E. coli, lyophilized powder, suitable for cell culture
别名:
IL-3, mIL-3, 白细胞介素3 来源于小鼠
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关于此项目
Biological source:
mouse
Recombinant:
expressed in E. coli
Assay:
≥98% (SDS-PAGE)
Form:
lyophilized powder
Mol wt:
15.1 kDa
Impurities:
≤1.000 EU/μg
产品名称
白细胞介素3 来源于小鼠, IL-3, recombinant, expressed in E. coli, lyophilized powder, suitable for cell culture
biological source
mouse
recombinant
expressed in E. coli
assay
≥98% (SDS-PAGE)
form
lyophilized powder
potency
0.01-0.1 ng/mL ED50/EC50
quality
endotoxin tested
mol wt
15.1 kDa
packaging
pkg of 10 and 50 μg
technique(s)
cell culture | mammalian: suitable
impurities
≤1.000 EU/μg
color
white to yellow
UniProt accession no.
storage temp.
−20°C
Quality Level
General description
白介素3是一种造血生长因子，可刺激嗜碱性粒细胞的发育并触发组胺、IL-4和IL-6的释放。它改善单核细胞和巨噬细胞的活化和吞噬作用，增强嗜酸性粒细胞的分泌功能。白介素3促进内皮细胞增殖和迁移。
Application
来自小鼠的白介素3已被用于确定5-脂肪氧合酶产物白细胞三烯C4（LTC4）的形成。它还被用作RPMI 1640细胞转染培养基的成分。
Biochem/physiol Actions
白细胞介素-3 (IL-3) 是一种多功能蛋白，最初称为集落形成单位刺激活性 (CFU-SA)，由活化的 T 淋巴细胞产生。IL-3 在多能造血祖细胞的早期发育过程中支持多系集落的形成。IL-3 可诱导琼脂悬浮的骨髓细胞形成巨噬细胞、中性粒细胞、肥大细胞和巨核细胞。IL-3 还与 IL-2 相互作用以刺激 T 淋巴细胞的生长并诱导活化 B 细胞分泌 IgG。IL-3 的其他同义词包括全特异性血细胞生成素、多集落刺激因子、肥大细胞生长因子、爆发性促进活性、产生组胺的细胞刺激因子、P 细胞刺激因子和 WEHI-3 因子。
Physical form
用 0.5 mg 牛血清白蛋白冻干。无菌过滤通过 0.2μm 型过滤器。
Analysis Note
通过剂量依赖性刺激小鼠 M-NFS-60 细胞增殖测定生物活性。
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
法规信息
常规特殊物品
低风险生物材料
此项目有
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