I4777
干扰素-γ 来源于小鼠
≥98% (SDS-PAGE), recombinant, expressed in E. coli, lyophilized powder, suitable for cell culture
别名:
IFN-γ
产品名称
干扰素-γ 来源于小鼠, ≥98% (SDS-PAGE), recombinant, expressed in E. coli, lyophilized powder, suitable for cell culture
biological source
mouse
recombinant
expressed in E. coli
assay
≥98% (SDS-PAGE)
form
lyophilized powder
mol wt
protein 15.6 kDa
packaging
pkg of 0.1 mg
technique(s)
cell culture | mammalian: suitable
impurities
endotoxin, tested
color
white
solubility
water: soluble 1.000 mL, clear, colorless
UniProt accession no.
storage temp.
−20°C
Quality Level
Gene Information
mouse ... Ifng(15978)
Analysis Note
重组小鼠 IFN-γ 的生物学活性通过其抑制鼠 WEHI-279 细胞增殖的能力进行测定。
Application
小鼠干扰素-γ 已用于：
- 体外 BMDC（骨髓源性树突状细胞）、BMM（骨髓源性巨噬细胞）和 CD11c + （CD11 抗原样家族成员 c）肺巨噬细胞的刺激
- 刺激小鼠巨噬细胞，诱导产生亚硝酸盐和硝酸盐
- 检查 CCAAT/增强子结合蛋白 β（C/EBPβ）介导的前列腺素合成酶在神经炎症中表达的变化
Biochem/physiol Actions
干扰素-γ (interferon-γ) 在天然免疫和获得性免疫应答中发挥重要作用，并有助于防御细菌感染、二型酵母和一些病毒感染。
Physical form
从 0.2 μm 过滤缓冲液冻干。基于蛋白质含量的包装尺寸。
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
法规信息
常规特殊物品
此项目有
Sergio Arias-Negrete et al.
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S N Vogel et al.
Infection and immunity, 38(2), 681-685 (1982-11-01)
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P W Gray et al.
Proceedings of the National Academy of Sciences of the United States of America, 80(19), 5842-5846 (1983-10-01)
The murine immune interferon (IFN-gamma) gene was cloned and expressed under control of the simian virus 40 early promoter in the monkey COS-1 cell line. A protein is secreted from these cells having the biological, antigenic, and biochemical characteristics of
Shaoxi Yan et al.
Mediators of inflammation, 2021, 9976912-9976912 (2021-09-01)
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Tatiana Cheusova et al.
Genes & development, 20(13), 1800-1816 (2006-07-05)
The release of Agrin by motoneurons activates the muscle-specific receptor tyrosine kinase (MuSK) as the main organizer of subsynaptic specializations at the neuromuscular junction. MuSK downstream signaling is largely undefined. Here we show that protein kinase CK2 interacts and colocalizes
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