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Merck
CN

I5286

人白介素-3 来源于小鼠

Carrier free, recombinant, expressed in E. coli, ≥98% (SDS-PAGE), suitable for cell culture

别名:

HCGF P-cell stimulation factorIL-3 MGC79398, Interleukin-3, MCGF (Mast cell growth factor)Multi-CSF, MGC79399

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关于此项目

UNSPSC Code:
12352202
NACRES:
NA.32
MDL number:
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biological source

mouse

Quality Segment

recombinant

expressed in E. coli

assay

≥98% (SDS-PAGE)

form

lyophilized

mol wt

15.1 kDa

packaging

pkg of 10 μg

technique(s)

cell culture | mammalian: suitable

impurities

<0.1 EU/μg endotoxin, tested

color

white

UniProt accession no.

shipped in

dry ice

storage temp.

−20°C

Gene Information

mouse ... IL3(16187)

General description

IL-3 is a hematopoietic growth factor that promotes the survival, differentiation and proliferation of committed progenitor cells of the megakaryocyte, granulocyte-macrophage, erythroid, eosinophil, basophil and mast cell lineages. Produced by T cells, mast cells and eosinophils, IL-3 enhances thrombopoieses, phagocytosis, and antibody-mediated cellular cytotoxicity. Its ability to activate monocytes suggests that IL-3 may have additional immunoregulatory roles. Many of the IL-3 activities depend upon co-stimulation with other cytokines. IL-3 is species-specific, variably glycosylated cytokine. Recombinant murine IL-3 is a 15.1 kDa globular protein containing 135 amino acid residues.

Biochem/physiol Actions

IL-3 is a hematopoietic growth factor that promotes the survival, differentiation and proliferation of committed progenitor cells of the megakaryocyte, granulocyte-macrophage, erythroid, eosinophil, basophil and mast cell lineages. Recombinant murine IL-3 is a 15.1 kDa globular protein containing 135 amino acid residues.

Preparation Note

Centrifuge the vial prior to opening. Reconstitute in water to a concentration of 0.1-1.0 mg/ml. Do not vortex. This solution can be stored at 2-8°C for up to 1 week. For extended storage, it is recommended to further dilute in a buffer containing a stabilizer (example 5% Trehalose) and store in working aliquots at -20°C to -80°C.


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存储类别

11 - Combustible Solids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable



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分析证书(COA)

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