I5627
异丙肾上腺素 盐酸盐
≥98.5% (TLC), powder, β-adrenoceptor agonist
别名:
(±)-异丙肾上腺素 盐酸盐, 1-(3′,4′-二羟基苯基)-2-异丙基氨基乙醇 盐酸盐, N-异丙基-DL-去甲肾上腺素 盐酸盐
Product Name
异丙肾上腺素 盐酸盐,
质量水平
mp
165-175 °C (dec.) (lit.)
创始人
Sanofi Aventis
SMILES字符串
Cl.CC(C)NCC(O)c1ccc(O)c(O)c1
InChI
1S/C11H17NO3.ClH/c1-7(2)12-6-11(15)8-3-4-9(13)10(14)5-8;/h3-5,7,11-15H,6H2,1-2H3;1H
InChI key
IROWCYIEJAOFOW-UHFFFAOYSA-N
基因信息
human ... ADRB1(153), ADRB2(154), ADRB3(155)
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生化/生理作用
β-肾上腺素受体激活剂；增加胞质cAMP。
特点和优势
该化合物是由Sanofi Aventis研发。想要浏览其他由制药公司开发的化合物以及已批准物/候选药物清单， 请单击此处。
其他说明
仅供研究使用
储存分类代码
11 - Combustible Solids
WGK
WGK 2
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
dust mask type N95 (US), Eyeshields, Gloves
历史批次信息供参考:
分析证书(COA)
Lot/Batch Number
Na Tian et al.
Diabetes, 69(7), 1355-1367 (2020-04-17)
Obesity has recently become a prevalent health threat worldwide. Although emerging evidence has suggested a strong link between the pentose phosphate pathway (PPP) and obesity, the role of transketolase (TKT), an enzyme in the nonoxidative branch of the PPP that
Eric M Jones et al.
eLife, 9 (2020-10-22)
The >800 human G protein-coupled receptors (GPCRs) are responsible for transducing diverse chemical stimuli to alter cell state- and are the largest class of drug targets. Their myriad structural conformations and various modes of signaling make it challenging to understand
Michael Schwarzl et al.
Critical care medicine, 41(12), e401-e410 (2013-08-22)
We tested whether mild hypothermia impacts on circulatory and respiratory dysfunction during experimental endotoxemia. Randomized controlled prospective experimental study. Large animal facility, Medical University of Graz, Austria. Thirteen anesthetized and mechanically ventilated pigs. Lipopolysaccharide was administered for 4 hours. With
Aaron M Ring et al.
Nature, 502(7472), 575-579 (2013-09-24)
G-protein-coupled receptors (GPCRs) are integral membrane proteins that have an essential role in human physiology, yet the molecular processes through which they bind to their endogenous agonists and activate effector proteins remain poorly understood. So far, it has not been
Roshanak Irannejad et al.
Nature, 495(7442), 534-538 (2013-03-22)
A long-held tenet of molecular pharmacology is that canonical signal transduction mediated by G-protein-coupled receptor (GPCR) coupling to heterotrimeric G proteins is confined to the plasma membrane. Evidence supporting this traditional view is based on analytical methods that provide limited
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