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经验公式(希尔记法):
C19H30O5
化学文摘社编号:
分子量:
338.44
UNSPSC Code:
12352204
PubChem Substance ID:
NACRES:
NA.25
MDL number:
产品名称
艾地苯醌, ≥98% (HPLC)
SMILES string
O=C(C(OC)=C1OC)C(CCCCCCCCCCO)=C(C)C1=O
InChI key
JGPMMRGNQUBGND-UHFFFAOYSA-N
InChI
1S/C19H30O5/c1-14-15(12-10-8-6-4-5-7-9-11-13-20)17(22)19(24-3)18(23-2)16(14)21/h20H,4-13H2,1-3H3
assay
≥98% (HPLC)
form
powder
solubility
methanol: 50 mg/mL, clear to slightly hazy
storage temp.
room temp
Quality Level
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Application
艾地苯醌已用于:
- 处理用于药物治疗测定的突变肌纤蛋白 (mMYOC)细胞
- 验证 C2C12 二次细胞筛选测定
- 处理肥胖小鼠,测试艾地苯醌和 CoQ10 是否直接结合过氧化物酶体增殖物激活受体(PPAR)LBD、His 标记的 PPAR αδ 和γ LBD。
Biochem/physiol Actions
一种短链辅酶 Q 类似物,可通过介导电子从 N2 转移到氧来增强超氧化物的形成。
艾地苯醌用于治疗患有 Leber′遗传性视神经病变 (LHON)的青少年和成人的视力障碍。它可用作抗氧化剂。它有助于保护心肌免于氧化应激。
General description
艾地苯醌是一种短链苯醌类药物。
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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