I7016
H-7 dihydrochloride
≥98% (HPLC)
别名:
1-(5-Isoquinolinylsulfonyl)-2-methylpiperazine dihydrochloride, Isoquinoline-5-sulfonic 2-methyl-1-piperazide dihydrochloride
登录 查看组织和合同定价。
选择尺寸
关于此项目
经验公式（希尔记法）:
C14H17N3O2S · 2HCl
化学文摘社编号:
分子量:
364.29
UNSPSC Code:
12352200
NACRES:
NA.77
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
5840763
产品名称
H-7 dihydrochloride, ≥98% (HPLC)
Quality Level
InChI
1S/C14H17N3O2S.2ClH/c1-11-9-16-7-8-17(11)20(18,19)14-4-2-3-12-10-15-6-5-13(12)14;;/h2-6,10-11,16H,7-9H2,1H3;2*1H
SMILES string
Cl.Cl.CC1CNCCN1S(=O)(=O)c2cccc3cnccc23
InChI key
OARGPFMFRLLKPF-UHFFFAOYSA-N
assay
≥98% (HPLC)
form
powder
solubility
H2O: 20 mg/mL
storage temp.
2-8°C
Gene Information
human ... PRKCA(5578), PRKCB(5579), PRKCD(5580), PRKCE(5581), PRKCG(5582), PRKCH(5583), PRKCI(5584)
正在寻找类似产品? 访问 产品对比指南
Application
H-7 dihydrochloride has been used to study H-7-induced inhibition of contractility in rat embryo fibroblasts (REF52) cells and acts as a kinase inhibitor.
Biochem/physiol Actions
Inhibitor of cyclic nucleotide dependent protein kinase (PKA) and protein kinase C.
Disclaimer
Light sensitive
General description
H-7 dihydrochloride blocks human immunodeficiency virus (HIV-1) replication in MOLT-4 (clone No. 8) cell line. It increases the secretion of interleukin 1β (IL-1β).
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
A new dimension in retrograde flow: centripetal movement of engulfed particles
Caspi A, et al.
Biophysical Journal, 81(4), 1990-2000 (2001)
Mechanism of inhibitory effect of glycyrrhizin on replication of human immunodeficiency virus (HIV)
Ito M, et al.
Antiviral Research, 10(6), 289-298 (1988)
Endotoxin in Health and Disease, 289-298 (1999)
Molecular diversity of cell-matrix adhesions
Zamir E, et al.
Journal of Cell Science, 112(11), 1655-1669 (1999)
Christopher J Groten et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 35(6), 2747-2765 (2015-02-13)
It is unknown whether neurons can dynamically control the capacity for secretion by promptly changing the number of plasma membrane voltage-gated Ca(2+) channels. To address this, we studied peptide release from the bag cell neurons of Aplysia californica, which initiate
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系客户支持