biological source
human
recombinant
expressed in E. coli
assay
≥95% (SDS-PAGE)
form
lyophilized powder
potency
<0.5 ng/mL ED50
quality
endotoxin tested
packaging
pkg of 4 μg
technique(s)
cell culture | mammalian: suitable
impurities
<0.1 EU/μg
UniProt accession no.
shipped in
dry ice
storage temp.
−20°C
Quality Level
Biochem/physiol Actions
白介素3(IL-3)是一种多功能蛋白,起初被称为克隆形成单位刺激活性(CFU-SA),由活化的T淋巴细胞产生。IL-3在多能造血祖细胞的早期发育中可支持多谱系克隆的形成。IL-3已显示出可从琼脂悬浮的骨髓细胞诱导巨噬细胞、嗜中性粒细胞、肥大细胞和巨核细胞的克隆形成。IL-3也可与IL-2发生互作,以刺激T淋巴细胞的生长并诱导活化B细胞分泌IgG。IL-3的其他同义词包括泛特异性造血素、多克隆刺激因子、肥大细胞生长因子、爆发促进活性、组胺生成细胞刺激因子、P细胞刺激因子和WEHI-3因子。
白细胞介素3是由活化的T淋巴细胞产生的一种多功能蛋白。 IL-3在多能造血祖细胞的早期发育中可支持多谱系克隆的形成。IL-3还与IL-2相互作用,以刺激T淋巴细胞的生长并诱导活化B细胞分泌IgG。
Physical form
Lyophilized from a 0.2 μm filtered solution.
Other Notes
One unit is the amount of IL-3 required to induce half-maximal incorportion of 3H thymidine. Activity also is expressed in Reference units (NIBSC reference preparation for IL-3 code 88/87).
存储类别
12 - Non Combustible Liquids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)
法规信息
常规特殊物品
此项目有
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商品
Interleukins, released from leukocytes, include IL-1β playing crucial roles in inflammation, immune responses, and anti-tumor immunity.
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