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Merck
CN

I8000

2-碘苯甲酸

≥98% (TLC)

别名:

IBA

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关于此项目

线性分子式:
OIC6H4CO2H
化学文摘社编号:
分子量:
264.02
NACRES:
NA.26
PubChem Substance ID:
UNSPSC Code:
12352209
EC Number:
206-159-4
MDL number:
Beilstein/REAXYS Number:
1939973
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产品名称

2-碘苯甲酸,

InChI key

IFPHDUVGLXEIOQ-UHFFFAOYSA-N

InChI

1S/C7H5IO3/c9-7(10)5-3-1-2-4-6(5)8-11/h1-4H,(H,9,10)

SMILES string

OC(=O)c1ccccc1[I]=O

assay

≥98% (TLC)

form

powder

color

white to off-white

mp

230 °C (dec.) (lit.)

storage temp.

−20°C

Quality Level

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Application

色氨酸肽键断裂。

Biochem/physiol Actions

碘苯甲酸 (IBA) 可用于研究酶的结构和活性。IBA 用作氧化剂,氧化邻近巯基为酶内的二硫化物(半胱氨酸残基),导致其失活或构象变化。IBA 也用于裂解色氨酸肽键。

pictograms

Exclamation mark

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

存储类别

11 - Combustible Solids

wgk

WGK 3

ppe

dust mask type N95 (US), Eyeshields, Gloves


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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J M Souza et al.
Archives of biochemistry and biophysics, 360(2), 187-194 (1998-12-16)
Rabbit muscle glyceraldehyde-3-phosphate dehydrogenase (GAPDH) was inactivated by peroxynitrite under biologically relevant conditions. The decrease of enzymatic activity followed an exponential function, and the concentration of peroxynitrite needed to inactivate 50% of 7 microM GAPDH (IC50) was 17 microM. Hydroxyl
R J Duhe et al.
The Journal of biological chemistry, 269(10), 7290-7296 (1994-03-11)
The calmodulin binding domain of the type I adenylyl cyclase has recently been identified as an amino acid sequence (residues 495-522) that contains 2 cysteine residues. Therefore, we examined the effect of several sulfhydryl reagents on the calmodulin sensitivity of
S P Fling et al.
Current eye research, 7(2), 191-199 (1988-02-01)
Bovine retinal S-antigen was cleaved by three chemical cleavage procedures including o-iodosobenzoic acid (IBA), mile acid and cyanogen bromide. The resultant peptides were used to study antibody-defined epitopes. Treatment with IBA, which cleaves primarily at tryptophanyl peptide bonds, produced at
Susanne Müller et al.
Toxicology letters, 200(1-2), 53-58 (2010-11-03)
Developing potent detoxification strategies for prophylaxis and therapy against organophosphate (OP) intoxication still represents a challenging task. Clinical application of numerous investigated substances including enzymes and low molecular scavengers like metal ions or nucleophiles could not yet be realised due
I Locklear et al.
Neuroscience, 35(3), 707-713 (1990-01-01)
A previously developed model of exercise-induced muscle contracture using iodoacetate to inhibit glyceraldehyde-3-phosphate dehydrogenase in rat hindlimb muscles produced selective type II myofiber damage. Utilizing a modification of the same model system, rats were given intra-aortic ortho-iodosobenzoic acid (700 nmol/kg

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