应用
兔血清IgG已被用于:
- 作为参考物质、标准品或阻断剂,适用于许多免疫检测,包括斑点印迹、ELISA、蛋白质免疫印迹、IEP和免疫扩散检测
- 阿蒂斯反应
- 染色质免疫沉淀
生化/生理作用
免疫球蛋白G(IgG)可调节免疫应答,如吞噬作用,并且还与自身免疫疾病的发展有关。 IgG1可调节小鼠的补体结合。
外形
0.01 M磷酸盐缓冲液(pH 7.2,含有15 mM叠氮化钠)溶液
制备说明
从合并的正常兔血清中分级纯化兔IgG
分析说明
免疫电泳(IEP)被用于鉴定兔IgG。与抗兔全血清和抗兔IgG相比,在γ区有一条主要的沉淀弧。与抗兔全血清相比,可能存在较小的γ弧
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储存分类代码
12 - Non Combustible Liquids
WGK
WGK 2
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
低风险生物材料
此项目有
历史批次信息供参考:
分析证书(COA)
Lot/Batch Number
Frances Rena Bahjat et al.
Arthritis and rheumatism, 58(5), 1433-1444 (2008-04-29)
To assess whether R788, an orally bioavailable small molecule inhibitor of spleen tyrosine kinase (Syk)-dependent signaling, could modulate disease in lupus-prone (NZB x NZW)F1 (NZB/NZW) mice via inhibition of Fc receptor (FcR) and B cell receptor signaling. R788 was administered
Elena Matveeva et al.
Cell discovery, 2, 15046-15046 (2016-07-28)
Specialized chromatin structures such as nucleosomes with specific histone modifications decorate exons in eukaryotic genomes, suggesting a functional connection between chromatin organization and the regulation of pre-mRNA splicing. Through profiling the functional location of Poly (ADP) ribose polymerase, we observed
Aluya R Oseghale et al.
Blood cells, molecules & diseases, 79, 102345-102345 (2019-07-28)
Pharmacologic induction of fetal hemoglobin (HbF) is an effective strategy for treating sickle cell disease (SCD) by ameliorating disease severity. Hydroxyurea is the only FDA-approved agent that induces HbF, but significant non-responders and requirement for frequent monitoring of blood counts
Mhairi Laird et al.
Endocrinology, 158(4), 920-935 (2017-03-23)
Androgens are essential for the normal function of mature antral follicles but also have a role in the early stages of follicle development. Polycystic ovary syndrome (PCOS), the most common cause of anovulatory infertility, is characterized by androgen excess and
Lily Chien Wang et al.
DNA repair, 7(12), 1973-1981 (2008-09-13)
Fanconi anemia (FA) is a recessive genetic disorder characterized by hypersensitivity to crosslinking agents that has been attributed to defects in DNA repair and/or replication. FANCD2 and the FA core complex bind to chromatin during DNA replication; however, the role
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