应用
兔血清IgG已被用于：
- 作为参考物质、标准品或阻断剂，适用于许多免疫检测，包括斑点印迹、ELISA、蛋白质免疫印迹、IEP和免疫扩散检测
- 阿蒂斯反应
- 染色质免疫沉淀
生化/生理作用
免疫球蛋白G（IgG）可调节免疫应答，如吞噬作用，并且还与自身免疫疾病的发展有关。 IgG1可调节小鼠的补体结合。
外形
0.01 M磷酸盐缓冲液（pH 7.2，含有15 mM叠氮化钠）溶液
制备说明
从合并的正常兔血清中分级纯化兔IgG
分析说明
免疫电泳（IEP）被用于鉴定兔IgG。与抗兔全血清和抗兔IgG相比，在γ区有一条主要的沉淀弧。与抗兔全血清相比，可能存在较小的γ弧
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储存分类代码
12 - Non Combustible Liquids
WGK
WGK 2
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
低风险生物材料
历史批次信息供参考:
分析证书(COA)
Lot/Batch Number
Frances Rena Bahjat et al.
Arthritis and rheumatism, 58(5), 1433-1444 (2008-04-29)
To assess whether R788, an orally bioavailable small molecule inhibitor of spleen tyrosine kinase (Syk)-dependent signaling, could modulate disease in lupus-prone (NZB x NZW)F1 (NZB/NZW) mice via inhibition of Fc receptor (FcR) and B cell receptor signaling. R788 was administered
Elena Matveeva et al.
Cell discovery, 2, 15046-15046 (2016-07-28)
Specialized chromatin structures such as nucleosomes with specific histone modifications decorate exons in eukaryotic genomes, suggesting a functional connection between chromatin organization and the regulation of pre-mRNA splicing. Through profiling the functional location of Poly (ADP) ribose polymerase, we observed
Mhairi Laird et al.
Endocrinology, 158(4), 920-935 (2017-03-23)
Androgens are essential for the normal function of mature antral follicles but also have a role in the early stages of follicle development. Polycystic ovary syndrome (PCOS), the most common cause of anovulatory infertility, is characterized by androgen excess and
Aluya R Oseghale et al.
Blood cells, molecules & diseases, 79, 102345-102345 (2019-07-28)
Pharmacologic induction of fetal hemoglobin (HbF) is an effective strategy for treating sickle cell disease (SCD) by ameliorating disease severity. Hydroxyurea is the only FDA-approved agent that induces HbF, but significant non-responders and requirement for frequent monitoring of blood counts
Gregory P Priebe et al.
Journal of immunology (Baltimore, Md. : 1950), 181(7), 4965-4975 (2008-09-20)
In a murine model of acute fatal pneumonia, we previously showed that nasal immunization with a live-attenuated aroA deletant of Pseudomonas aeruginosa strain PAO1 elicited LPS serogroup-specific protection, indicating that opsonic Ab to the LPS O Ag was the most
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