biological source
rat
Quality Segment
recombinant
expressed in CHO cells
assay
≥95%
form
lyophilized powder
mol wt
~20 kDa
packaging
pkg of 1 vial
concentration
≥100000 units/mL
technique(s)
cell culture | mammalian: suitable
UniProt accession no.
shipped in
dry ice
storage temp.
−70°C
Gene Information
rat ... Ifnb1(24481)
Biochem/physiol Actions
Interferon β belongs to the type 1 interferon family pf proteins. It is also needed for the inhibition of tumor cell growth via cell death, S-phase increase and mediating differentiation. It is also important for bone homeostasis.
Cytokine with anti-viral, anti-proliferative, immunoregulatory, and proinflammatory activities.
Physical form
Lyophilized from phosphate buffered saline (PBS) containing 125 mM trehalose.
Analysis Note
The biological activity is determined in the cytopathic effect inhibition assay using rat epithelial-like (RATEC) cells with vesicular stomatitis virus (VSV). The cytopathic effect of 50% is produced with approximately 1 unit/ml interferon. Since there is no international rat interferon β standard, units are determined with respect to the NIH international standard reference for mouse interferon α/β.
存储类别
13 - Non Combustible Solids
怎么回事？
WGK 1
闪点 (F)
Not applicable
闪点 (°C)
Not applicable
PPE（个人防护设备）
Eyeshields, Gloves, type N95 (US)