J3955
JTC-801
≥98% (HPLC)
别名:
N-(4-amino-2-methylquinolin-6-yl)-2-(4-ethylphenoxymethyl)benzamide hydrochloride
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关于此项目
经验公式（希尔记法）:
C26H25N3O2 · HCl
化学文摘社编号:
分子量:
447.96
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352200
MDL number:
InChI
1S/C26H25N3O2.ClH/c1-3-18-8-11-21(12-9-18)31-16-19-6-4-5-7-22(19)26(30)29-20-10-13-25-23(15-20)24(27)14-17(2)28-25;/h4-15H,3,16H2,1-2H3,(H2,27,28)(H,29,30);1H
SMILES string
Cl.CCc1ccc(OCc2ccccc2C(=O)Nc3ccc4nc(C)cc(N)c4c3)cc1
InChI key
NQLIYKXNAXKMBL-UHFFFAOYSA-N
assay
≥98% (HPLC)
form
powder
storage condition
desiccated
color
tan
solubility
DMSO: ≥20 mg/mL
storage temp.
2-8°C
Quality Level
Biochem/physiol Actions
JTC-801 is a nociceptin/orphanin FQ peptide (NOP) receptor antagonist.
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2
存储类别
11 - Combustible Solids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
G Delaney et al.
Journal of neuroendocrinology, 24(12), 1527-1541 (2012-07-28)
Central nociceptin/orphanin FQ (N/OFQ)-expressing neurones are abundantly expressed in the hypothalamus and limbic system and are implicated in the regulation of activity of the hypothalamic-pituitary-adrenal axis (HPA) and stress responses. We investigated the role of the endogenous N/OFQ receptor (NOP)
Keiichi Hiramoto et al.
Photodermatology, photoimmunology & photomedicine, 33(2), 84-91 (2017-01-01)
We previously reported that ultraviolet (UV) A eye irradiation reduces the ulcerative colitis induced by dextran sodium sulfate (DSS). This study examined the effects of UVA on colon carcinoma induced by azoxymethane (AOM) and DSS. We irradiated the eyes of
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