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Merck
CN

K1127

肯普肽 乙酸盐

≥95% (HPLC), powder

别名:

磷酸盐受体肽

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关于此项目

经验公式(希尔记法):
C32H61N13O9 · xC2H4O2
化学文摘社编号:
分子量:
771.91 (free base basis)
UNSPSC Code:
12352200
PubChem Substance ID:
Beilstein/REAXYS Number:
6263936
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InChI

1S/C32H61N13O9.C2H4O2/c1-16(2)12-19(33)26(50)42-21(9-7-11-39-32(36)37)29(53)43-20(8-6-10-38-31(34)35)28(52)41-18(5)25(49)45-23(15-46)30(54)44-22(13-17(3)4)27(51)40-14-24(47)48;1-2(3)4/h16-23,46H,6-15,33H2,1-5H3,(H,40,51)(H,41,52)(H,42,50)(H,43,53)(H,44,54)(H,45,49)(H,47,48)(H4,34,35,38)(H4,36,37,39);1H3,(H,3,4)/t18-,19-,20-,21-,22-,23-;/m0./s1

SMILES string

CC(O)=O.[H]N[C@@H](CC(C)C)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCCNC(N)=N)C(N[C@H](C(N[C@@H](CO)C(N[C@@H](CC(C)C)C(NCC(O)=O)=O)=O)=O)C)=O)=O)=O

InChI key

WRTDQEIEUYKAKV-PXILYFGCSA-N

assay

≥95% (HPLC)

form

powder

color

white

solubility

H2O: 20 mg/mL

storage temp.

−20°C

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存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

法规信息

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分析证书(COA)

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L Belloni-Olivi et al.
The Biochemical journal, 315 ( Pt 2), 401-406 (1996-04-15)
In immature rat microvessels, endothelial cells and glioma cells, exposure to lead results in an increase in the level of protein kinase C in membranes. In this paper we have extended these studies to human erythrocytes and, in addition, studied
Role of multiple basic residues in determining the substrate specificity of cyclic AMP-dependent protein kinase.
B E Kemp et al.
The Journal of biological chemistry, 252(14), 4888-4894 (1977-07-25)
N-terminal protein sequencing for special applications.
Philip J Jackson
Methods in molecular biology (Clifton, N.J.), 211, 287-300 (2002-12-20)
Masatake Sano et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 794(1), 149-156 (2003-07-31)
Micellar electrokinetic chromatography (MEKC) with laser-induced fluorescence (LIF) detection has been developed for a protein kinase assay. This protein kinase assay could readily determine the phosphorylation activity of substrate peptide kemptide using cAMP-dependent protein kinase (PKA) as a model enzyme.
G Tortora et al.
Proceedings of the National Academy of Sciences of the United States of America, 88(5), 2011-2015 (1991-03-01)
A marked decrease in the type I cAMP-dependent protein kinase regulatory subunit (RI alpha) and an increase in the type II protein kinase regulatory subunit (RII beta) correlate with growth inhibition and differentiation induced in a variety of types of

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