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Merck
CN

K113

Ketamine hydrochloride/xylazine hydrochloride solution

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化学文摘社编号:
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352116
MDL number:
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InChI

1S/C13H16ClNO.C12H16N2S.2ClH/c1-15-13(9-5-4-8-12(13)16)10-6-2-3-7-11(10)14;1-9-5-3-6-10(2)11(9)14-12-13-7-4-8-15-12;;/h2-3,6-7,15H,4-5,8-9H2,1H3;3,5-6H,4,7-8H2,1-2H3,(H,13,14);2*1H

SMILES string

Cl.Cl.Cc1cccc(C)c1NC2=NCCCS2.CNC3(CCCCC3=O)c4ccccc4Cl

InChI key

IYJHJWJNWIPQFJ-UHFFFAOYSA-N

form

solution

drug control

USDEA Schedule III; stupéfiant (France); regulated under CDSA - not available from Sigma-Aldrich Canada; psicótropo (Spain)

color

colorless

storage temp.

2-8°C

Quality Level

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Biochem/physiol Actions

This is a solution of ketamine hydrochloride, an NMDA receptor antagonist, and xylazine hydrochloride, an α2- adrenergic receptor agonist.

Other Notes

Telephone orders are not accepted for this product.

仅试剂盒组分

产品编号
说明

  • Ketamine hydrochloride 80 mg/mL

  • Xylazine hydrochloride 12 mg/mL

存储类别

10 - Combustible liquids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter

法规信息

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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Azim Ullah Shamsul Islam et al.
Molecules (Basel, Switzerland), 25(19) (2020-10-04)
Physiological Glucocorticoids are important regulators of the immune system. Pharmacological GCs are in widespread use to treat inflammatory diseases. Adrenalectomy (ADX) has been shown to exacerbate renal injury through inflammation and oxidative stress that results in renal impairment due to
I Soltesz et al.
Journal of neurophysiology, 70(1), 97-116 (1993-07-01)
1. Intracellularly recorded low- and high-frequency (4-6 and 25-50 Hz, respectively), rhythmic, spontaneous membrane potential oscillations were investigated in pyramidal neurons of the rat hippocampus in vivo, during theta (theta, 4-6 Hz) electroencephalographic (EEG) activity, under ketamine-xylazine anesthesia. 2. The
Ehsan Saboory et al.
Experimental physiology, 105(5), 783-792 (2020-02-14)
What is the central question of this study? Do changes in levels of angiogenesis-related mediators [vascular endothelial growth factor-A (VEGF-A), thrombospondin-1 (TSP-1) and nuclear factor-κB (NF-κB)] in the sciatic nerve mediate diabetic neuropathy in the streptozotocin-induced type 1 diabetic male rat?
J P Gratton et al.
British journal of pharmacology, 114(3), 720-726 (1995-02-01)
1. In the present study, the precursors of endothelin-1, endothelin-2 and endothelin-3 were tested for their pressor and bronchoconstrictor properties in the anaesthetized guinea-pig. In addition, the effects of big-endothelin-1 and endothelin-1 were assessed under urethane or ketamine/xylazine anaesthesia. 2.
Liyuan Jiang et al.
Aging and disease, 11(3), 603-617 (2020-06-04)
The complex pathology of chronic thoracic spinal cord compression involves vascular and neuroarchitectural repair processes that are still largely unknown. In this study, we used synchrotron radiation microtomography (SRμCT) to quantitatively characterize the 3D temporal-spatial changes in the vascular and

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