K1385
KN-93
synthetic (organic), ≥98% (HPLC), Ca2+/calmodulin-dependent protein kinase II inhibitor, powder
别名:
N-[2-[N-(4-氯肉桂)-N-甲基氨基甲基]苯基]-N-(2-羟乙基)-4-甲氧基苯磺酰胺 磷酸盐, N-[2-[[[3-(4′-氯苯基)-2-丙烯基]甲基氨基]甲基]苯基]-N-(2-羟基乙基)-4′-甲氧基苯磺酰胺 磷酸盐
选择尺寸
关于此项目
产品名称
KN-93, ≥98% (HPLC)
SMILES string
OP(O)(O)=O.COc1ccc(cc1)S(=O)(=O)N(CCO)c2ccccc2CN(C)C\C=C\c3ccc(Cl)cc3
InChI key
NNKJTPOXLIILMB-IPZCTEOASA-N
InChI
1S/C26H29ClN2O4S.H3O4P/c1-28(17-5-6-21-9-11-23(27)12-10-21)20-22-7-3-4-8-26(22)29(18-19-30)34(31,32)25-15-13-24(33-2)14-16-25;1-5(2,3)4/h3-16,30H,17-20H2,1-2H3;(H3,1,2,3,4)/b6-5+;
biological source
synthetic (organic)
assay
≥98% (HPLC)
form
powder
color
white
solubility
DMSO: 1 mg/mL
H2O: soluble
storage temp.
2-8°C
Quality Level
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Application
- 作为抑制剂，阻挡αCaMKII (Ca2+/钙调蛋白依赖性蛋白激酶IIα)
- 作为CaMKII抑制剂，用于预处理海马脑片
- 在实验中处理细胞，修改细胞骨架(CSK)结构和功能
Biochem/physiol Actions
Disclaimer
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Which document(s) contains shelf-life or expiration date information for a given product?
If available for a given product, the recommended re-test date or the expiration date can be found on the Certificate of Analysis.
How do I get lot-specific information or a Certificate of Analysis?
The lot specific COA document can be found by entering the lot number above under the "Documents" section.
How do I find price and availability?
There are several ways to find pricing and availability for our products. Once you log onto our website, you will find the price and availability displayed on the product detail page. You can contact any of our Customer Sales and Service offices to receive a quote. USA customers: 1-800-325-3010 or view local office numbers.
What is the Department of Transportation shipping information for this product?
Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product.
Is Product No. K1385, KN-93, a salt?
Yes. It is the phosphate salt.
What is Product No. K1385, KN-93, soluble in?
Product K1385 is a water soluble form of KN-93, soluble in water at least at 5 mg/ml. It is also soluble in dimethyl sulfoxide (DMSO) to at least 1 mg/ml. Solutions and solid should be protected from light.
How to store solutions of Product No. K1385, KN-93?
Sigma has not performed solution stability studies. However, stock solutions may be stable for 1-3 months, if aliquotted and stored frozen at -20°C.
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