K1515
Anti-Kallikrein 11 antibody produced in rabbit
~1 mg/mL, affinity isolated antibody, buffered aqueous solution
别名:
Anti-Hippostasin, Anti-KLK11
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关于此项目
NACRES:
NA.41
UNSPSC Code:
12352203
Conjugate:
unconjugated
Clone:
polyclonal
Application:
IHC, WB
Citations:
3
biological source
rabbit
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous solution
mol wt
antigen ~35 kDa
species reactivity
rat, mouse, human
concentration
~1 mg/mL
technique(s)
immunohistochemistry: suitable, western blot: 1:500-1:1,000
UniProt accession no.
shipped in
dry ice
storage temp.
−20°C
Quality Level
Gene Information
human ... KLK11(11012)
mouse ... Klk11(56538)
rat ... Klk11(292849)
General description
The gene KLK11 (kallikrein 11) encodes a member of the kallikrein gene family. The gene is mapped to human chromosome 19q13.4. It is found to be highly expressed in the prostate. It has been found to be present in biological fluids and in serum of patients with various cancers. KLK11 is also found to be expressed in stomach, trachea, skin, and colon.
Immunogen
synthetic peptide corresponding to residues 68-82 of the human Kallikrein 11. This sequence is 86% identical in mouse and rat.
Biochem/physiol Actions
The gene KLK11 (kallikrein 11) encodes a putative serine protease that is overexpressed in prostate and ovarian cancer. It serves as a biomarker for prognosis of ovarian cancer. It can serve as a marker for distinguishing between prostate cancer and benign prostatic hyperplasia.
Physical form
solution in phosphate buffered saline, containing 0.02% sodium azide.
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存储类别
10 - Combustible liquids
wgk
nwg
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)
法规信息
新产品
此项目有
Human kallikrein 11: a new biomarker of prostate and ovarian carcinoma.
Diamandis EP
Cancer Research, 62, 295-300 (2002)
The usefulness of serum human kallikrein 11 for discriminating between prostate cancer and benign prostatic hyperplasia.
Nakamura T
Cancer Research, 63, 6543-6546 (2003)
Human kallikrein 11: an indicator of favorable prognosis in ovarian cancer patients.
Diamandis EP
Clinical Biochemistry, 37, 823-829 (2004)
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