K1750
α-酮戊二酸
≥98.5% (NaOH, titration)
别名:
2-氧代戊二酸, 2-氧化戊二酸
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关于此项目
线性分子式:
HOOCCH2CH2COCOOH
化学文摘社编号:
分子量:
146.10
UNSPSC Code:
12352204
NACRES:
NA.32
PubChem Substance ID:
EC Number:
206-330-3
Beilstein/REAXYS Number:
1705689
MDL number:
Quality Level
assay
≥98.5% (NaOH, titration)
form
powder
solubility
water: 100 mg/mL, clear to slightly hazy, colorless to faintly yellow
storage temp.
2-8°C
SMILES string
OC(=O)CCC(=O)C(O)=O
InChI
1S/C5H6O5/c6-3(5(9)10)1-2-4(7)8/h1-2H2,(H,7,8)(H,9,10)
InChI key
KPGXRSRHYNQIFN-UHFFFAOYSA-N
General description
αα-酮戊二酸(α-KG)在三羧酸循环中产生。
Application
αα-酮戊二酸(α-KG)已用于：
- 研究其在体外发酵系统中对猪粪菌群的影响
- 研究其对CD8+ T细胞的影响
- 在谷氨酸-草酰乙酸转氨酶(GOT)线粒体裂解物检测中作为底物
Biochem/physiol Actions
αα-酮戊二酸(α-KG)广泛应用于动物饲料、食品、制药和精细化工行业。
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signalword
Danger
hcodes
Hazard Classifications
Eye Dam. 1
存储类别
11 - Combustible Solids
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
Long Liu et al.
Journal of biotechnology, 164(1), 97-104 (2013-01-22)
Currently, α-ketoglutaric acid (α-KG) is industrially produced by multi-step chemical synthesis, which can cause heavy environmental pollution. Here we reported a simple one-step approach for the production of α-KG by transforming l-glutamic acid with an engineered l-amino acid deaminase (l-AAD)
G Biagi et al.
Journal of animal science, 85(5), 1184-1191 (2007-02-14)
Adding organic acids to piglet diets is known to be helpful in overcoming postweaning syndrome, and butyric acid is known to be the main energy source for the epithelial cells of the large intestine and the terminal ileum. This study
J Kitaura et al.
European journal of pediatrics, 158(5), 410-413 (1999-05-20)
Two cases of hyperinsulinaemic hypoglycaemia associated with persistent hyperammonaemia in unrelated infants of 7 days and 4 months of age are reported. Blood ammonia levels were 100-300 micromol/l (normal values <40 micromol/l). The hyperammonaemia was asymptomatic and not associated with
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| K1750-100G | 04061833868065 |
| K1750-1KG | 04061833868072 |