K2893
PAK1/CDC42, active, GST tagged human
PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution
别名:
MGC130000, MGC130001, PAKalpha
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关于此项目
NACRES:
NA.32
UNSPSC Code:
51111800
Specific activity:
40-53 nmol/min·mg
Assay:
≥70% (SDS-PAGE)
Recombinant:
expressed in baculovirus infected Sf9 cells
recombinant
expressed in baculovirus infected Sf9 cells
Quality Segment
product line
PRECISIO® Kinase
assay
≥70% (SDS-PAGE)
form
buffered aqueous glycerol solution
specific activity
40-53 nmol/min·mg
mol wt
~96 kDa
UniProt accession no.
shipped in
dry ice
storage temp.
−70°C
Gene Information
human ... PAK1(5058)
Biochem/physiol Actions
PAK1 is a member of the p21-activated kinases (PAKs) which have been implicated in the regulation of gene transcription, cell morphology, motility and apoptosis. PAKs are serine/threonine kinases which bind to and are activated by small GTPases, CDC42 (cell division cycle 42) and RAC. PAK1 belongs to the Group I PAKs which also includes PAK2 and PAK3. PAK1 is a key regulator of the actin cytoskeleton, adhesion and cell motility.
Physical form
Supplied in 50 mM Tris-HCl, pH 7.5, with 150 mM NaCl, 0.2 5mM DTT, 0.1 mM EGTA, 0.1 mM EDTA, 0.1 mM PMSF, and 25% glycerol.
Legal Information
PRECISIO is a registered trademark of Merck KGaA, Darmstadt, Germany
存储类别
10 - Combustible liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)