K3125
曲酸
≥98.5% (HPLC), powder, tyrosinase inhibitor
别名:
2-羟甲基-5-羟基-γ-吡喃酮, 5-羟基-2-羟甲基-4H-4-吡喃酮
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关于此项目
经验公式（希尔记法）:
C6H6O4
化学文摘社编号:
分子量:
142.11
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352106
EC Number:
207-922-4
MDL number:
Beilstein/REAXYS Number:
120895
产品名称
曲酸,
assay
≥98.5% (HPLC)
Quality Level
form
powder
mp
152-155 °C (lit.)
SMILES string
OCC1=CC(=O)C(O)=CO1
InChI
1S/C6H6O4/c7-2-4-1-5(8)6(9)3-10-4/h1,3,7,9H,2H2
InChI key
BEJNERDRQOWKJM-UHFFFAOYSA-N
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Application
曲酸已被用于：
- 作为豚鼠色素性远视 (PH) 中酪氨酸酶的抑制剂
- 作为引用抑制剂标准用于筛选酪氨酸酶抑制
- 作为 B16F10 黑色素瘤细胞中酪氨酸酶抑制的阳性对照
Biochem/physiol Actions
曲酸来源于曲霉菌属、醋酸杆菌属和青霉属等真菌。它通过抑制酪氨酸酶而使黑色素合成停止。用于皮肤美白化妆品的制备。然而，曲酸在化妆品中的使用很少，因为其在长期储存期间的不稳定性和细胞毒性导致皮肤刺激。它是一种抗氧化剂，对锰和锌的螯合起辐射保护作用。
酪氨酸酶抑制剂。
存储类别
11 - Combustible Solids
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
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全球贸易项目编号
| 货号 | GTIN |
|---|---|
| K3125-5G | 04061835557424 |
| K3125-25G | 04061833868423 |
| K3125-10G | 04061833868416 |
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