K3250
犬尿胺 二氢溴酸
monoamine oxidase substrate, fluorogenic, ≥97% (TLC), crystalline
别名:
3-（2-氨基苯基）-3-氧代丙胺
产品名称
犬尿胺 二氢溴酸, crystalline
方案
≥97% (TLC)
质量水平
表单
crystalline
溶解性
water: 50 mg/mL, clear to slightly hazy
储存温度
−20°C
SMILES字符串
Br.NCCC(=O)c1ccccc1N
InChI
1S/C9H12N2O.BrH/c10-6-5-9(12)7-3-1-2-4-8(7)11;/h1-4H,5-6,10-11H2;1H
InChI key
YUPVVZSYBUIDQR-UHFFFAOYSA-N
一般描述
单胺氧化酶底物
应用
二氢溴酸犬尿氨酸被用作单胺氧化酶的底物。
生化/生理作用
二氢溴酸犬尿氨酸是单胺氧化酶的底物。最终产物为荧光分光光度计在 380 nm 处测定的荧光可检测 4-羟基喹啉 (4-HOQ) 的形成。
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
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Berntssen MHG, et al.
Aquatic Toxicology (Amsterdam, Netherlands), 65(1), 55-72 (2003)
Magdalena S Nel et al.
Bioorganic chemistry, 69, 20-28 (2016-09-24)
In the present study a series of fifteen 2-heteroarylidene-1-indanone derivatives were synthesised and evaluated as inhibitors of recombinant human monoamine oxidase (MAO) A and B. These compounds are structurally related to series of heterocyclic chalcone derivatives which have previously been
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Li G, et al.
Metabolic Brain Disease, 30(6), 1505-1514 (2015)
Izaviany da Silva Schmitz et al.
Molecular biology reports, 46(2), 2285-2292 (2019-02-14)
Oxidative stress occurs due to an imbalance between antioxidant defenses and pro-oxidant agents in brain. This condition has been associated to the pathogenesis of several brain diseases; therefore, increasing the use of compounds that exert antioxidant activity. Thus, the objective
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Molecules (Basel, Switzerland), 24(3) (2019-02-01)
New N-acetyl/N-thiocarbamoylpyrazoline derivatives were designed and synthesized in high yields to assess their inhibitory activity and selectivity against human monoamine oxidase A and B. The most important chiral compounds were separated into their single enantiomers and tested. The impact of
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