K3643
PKAcγ, active, GST tagged human
PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution
别名:
KAPG, PKAr, cAPKr
重组
expressed in baculovirus infected Sf9 cells
质量水平
产品线
PRECISIO® Kinase
方案
≥70% (SDS-PAGE)
表单
buffered aqueous glycerol solution
比活
128-174 nmol/min·mg
分子量
~65 kDa
UniProt登记号
运输
dry ice
储存温度
−70°C
基因信息
human ... PRKACG(5568)
生化/生理作用
PKAcγ (protein kinase cAMP-activated catalytic subunit γ) is a catalytic isoform of cyclic adenosine monophosphate-dependent protein kinase. It is an intronless gene and has a testis-specific expression. It is involved in platelet biogenesis. Mutation in PKAcγ causes macrothrombocytopenia, an inherited thrombocytopenias.
外形
Supplied in 50 mM Tris-HCl, pH 7.5, with 150 mM NaCl, 0.2 5mM DTT, 0.1 mM EGTA, 0.1 mM EDTA, 0.1 mM PMSF, and 25% glycerol.
法律信息
PRECISIO is a registered trademark of Merck KGaA, Darmstadt, Germany
储存分类代码
10 - Combustible liquids
WGK
WGK 1
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)
法规信息
新产品
此项目有
Vladimir T Manchev et al.
Blood, 124(16), 2554-2563 (2014-07-26)
Macrothrombocytopenias are the most important subgroup of inherited thrombocytopenias. This subgroup is particularly heterogeneous because the affected genes are involved in various functions such as cell signaling, cytoskeleton organization, and gene expression. Herein we describe the clinical and hematological features
S J Beebe et al.
Molecular endocrinology (Baltimore, Md.), 4(3), 465-475 (1990-03-01)
Two different mammalian genes for the catalytic subunit (C) of cAMP-dependent protein kinase have previously been characterized (C alpha, C beta). In the present study, we report the molecular cloning of a third isoform of C, from a human testis
N Reinton et al.
Genomics, 49(2), 290-297 (1998-05-23)
Three different catalytic isoforms of cAMP-dependent protein kinase have been identified (C alpha, C beta, and C gamma). We report the cloning and characterization of the human and rhesus monkey genes encoding the testis-specific C gamma subunit. The human C
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