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Merck
CN

K3643

Sigma-Aldrich

PKAcγ, active, GST tagged human

PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution

别名:

KAPG, PKAr, cAPKr

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关于此项目

UNSPSC代码:
12352200
NACRES:
NA.32
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重组

expressed in baculovirus infected Sf9 cells

质量水平

产品线

PRECISIO® Kinase

方案

≥70% (SDS-PAGE)

表单

buffered aqueous glycerol solution

比活

128-174 nmol/min·mg

分子量

~65 kDa

UniProt登记号

运输

dry ice

储存温度

−70°C

基因信息

human ... PRKACG(5568)

生化/生理作用

PKAcγ (protein kinase cAMP-activated catalytic subunit γ) is a catalytic isoform of cyclic adenosine monophosphate-dependent protein kinase. It is an intronless gene and has a testis-specific expression. It is involved in platelet biogenesis. Mutation in PKAcγ causes macrothrombocytopenia, an inherited thrombocytopenias.

外形

Supplied in 50 mM Tris-HCl, pH 7.5, with 150 mM NaCl, 0.2 5mM DTT, 0.1 mM EGTA, 0.1 mM EDTA, 0.1 mM PMSF, and 25% glycerol.

法律信息

PRECISIO is a registered trademark of Merck KGaA, Darmstadt, Germany

储存分类代码

10 - Combustible liquids

WGK

WGK 1

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)

法规信息

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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Vladimir T Manchev et al.
Blood, 124(16), 2554-2563 (2014-07-26)
Macrothrombocytopenias are the most important subgroup of inherited thrombocytopenias. This subgroup is particularly heterogeneous because the affected genes are involved in various functions such as cell signaling, cytoskeleton organization, and gene expression. Herein we describe the clinical and hematological features
S J Beebe et al.
Molecular endocrinology (Baltimore, Md.), 4(3), 465-475 (1990-03-01)
Two different mammalian genes for the catalytic subunit (C) of cAMP-dependent protein kinase have previously been characterized (C alpha, C beta). In the present study, we report the molecular cloning of a third isoform of C, from a human testis
N Reinton et al.
Genomics, 49(2), 290-297 (1998-05-23)
Three different catalytic isoforms of cAMP-dependent protein kinase have been identified (C alpha, C beta, and C gamma). We report the cloning and characterization of the human and rhesus monkey genes encoding the testis-specific C gamma subunit. The human C

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