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Merck
CN

L0130

β-乳球蛋白 来源于牛奶

≥90% (PAGE), lyophilized powder

别名:

β-LG, Bos d 5, beta-LG

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化学文摘社编号:
UNSPSC Code:
12352202
EC Number:
232-928-9
NACRES:
NA.61
MDL number:
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产品名称

β-乳球蛋白 来源于牛奶, ≥90% (PAGE), lyophilized powder

biological source

bovine milk

assay

≥90% (PAGE)

form

lyophilized powder

UniProt accession no.

storage temp.

2-8°C

Quality Level

Gene Information

bovine ... LGB(280838)

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Analysis Note

可能不含叶酸结合蛋白;不推荐用于叶酸分析。

Application

来自牛奶的β-乳球蛋白用于测试对牛′s 奶过敏的儿童过敏原反应性 CD4 + CD25 + 调节性 T细胞。它还用于测试 Tween 20 从油 - 水和空气 - 水界面的β-乳球蛋白的竞争性置换。

General description

作为脂质运载蛋白家族的成员,β-乳球蛋白(βLg)是162个氨基酸的小蛋白质,分子量为∼18,400Da。它具有八链β-桶(链A-H),其后面是三转α-螺旋和最终 β-链(链I),其形成二聚化界面的一部分。
来自奶牛的牛奶含有蛋白质 β-乳球蛋白(BLG)。它天然存在于许多遗传变异体中,最普遍的牛变体是BLG A和BLG B。

Other Notes

含 β-乳球蛋白 A 和 B,可通过色谱法分离。

Preparation Note

结晶

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

法规信息

低风险生物材料
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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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The Competitive Displacement of ?-Lactoglobulin by Tween 20 from Oil-Water and Air-Water Interfaces
Peter J. Wilde, David C. Clark
Journal of Colloid and Interface Science, 155, 48-54 (1993)
Isabella Pali-Schöll et al.
Clinical and translational allergy, 12(2), e12125-e12125 (2022-02-17)
Growing up on a cattle farm and consuming raw cow's milk protects against asthma and allergies. We expect a cattle-specific protein as active component in this farm effect. Dust was collected from cattle and poultry stables and from mattresses of
Nicholas A Smith et al.
Brain, behavior, and immunity, 95, 122-141 (2021-03-12)
A number of studies have reported comorbidity of food allergies with various neuropsychiatric disorders, such as anxiety, depression, attention-deficit hyperactivity disorder, and autism. However, inconsistent results across clinical studies have left the association between food allergy and behavioral disorders inconclusive.
Rachana Pathak et al.
European biophysics journal : EBJ, 51(4-5), 335-352 (2022-05-17)
Amyloid crystals, a form of ordered protein aggregates documented relatively recently, have not been studied as extensively as amyloid fibres. This study investigates the formation of amyloid crystals with low frequency ultrasound (20 kHz) using β-lactoglobulin, as a model protein for
A Heinzmann et al.
International archives of allergy and immunology, 120(4), 280-286 (2000-01-21)
beta-Lactoglobulin (BLG) represents one of the major allergens causing cow's milk allergy (CMA) - a disease with a wide spectrum of clinical symptoms. The aim of this study was to evaluate sequential B cell epitopes of BLG by the Pin-ELISA

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