conjugate
FITC conjugate
form
buffered aqueous solution
extent of labeling
2.0-6.0 mol FITC per mol lectin
storage temp.
2-8°C
Quality Level
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General description
凝集素是糖类结合蛋白。番茄凝集素(LEA)强力结合聚乳糖胺寡糖。它是内皮和上皮细胞表面糖类物质的主要组分。
Application
番茄凝集素已用于：
- 免疫荧光染色
- 血管灌注定量
- 凝胶灌注评估
Biochem/physiol Actions
LEA 不具有血型特异性，但对 N-乙酰-β- D -氨基葡萄糖低聚物具有亲和力。凝集素是一种糖蛋白，含有约等量的蛋白质和碳水化合物，并被报道抑制来自 菜豆的植物血凝素的促有丝分裂活性 。这种凝集素结合内皮细胞，用于显示微血管。
凝集素具有抗癌、抗人免疫缺陷病毒（抗HIV）、抗微生物感染作用，并可抑制粘膜萎缩。它可减轻2型糖尿病和肥胖症，促进营养吸收和药物靶向。它可用于对动物脊髓和大脑中的血管树进行染色。凝集素可凝聚细胞，沉淀多糖和糖蛋白。
Packaging
按活性结合物毫克数出售。
Physical form
溶于 10 mM HEPES、0.15 MNaCl (pH 7.5)、含 0.1 mM Ca2+、0.08% 叠氮化钠和 5 mg/mLβ-环糊精。
Analysis Note
凝集活性以 μ 表示g/ml，并通过在 pH 7.3 的磷酸盐缓冲盐水中连续稀释 1 mg/mL 溶液测定。该活性是在 25℃ 下孵育 1 小时后凝集 2% 人红细胞悬液的最低浓度。
存储类别
12 - Non Combustible Liquids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
低风险生物材料
此项目有
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