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Merck
CN

L0636

来自 普通小麦 的凝集素(小麦)

BioReagent, suitable for cell culture, lyophilized powder

别名:

WGA, Wheat germ agglutinin

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关于此项目

NACRES:
NA.32
UNSPSC Code:
12352202
Form:
lyophilized powder
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产品名称

来自 普通小麦 的凝集素(小麦), BioReagent, suitable for cell culture, lyophilized powder

sterility

aseptically processed

product line

BioReagent

form

lyophilized powder

technique(s)

cell culture | mammalian: suitable

impurities

salt, essentially free

storage temp.

2-8°C

Quality Level

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Application

小麦来源凝集素已用于:
  • 与N-羟基琥珀酰亚胺(NHS)染料偶联
  • 抑制核输入
  • 抑制人类宫颈癌HeLa和SiHa细胞的核孔

Biochem/physiol Actions

WGA 不具有血型特异性,但具有与 N-乙酰基-β-D-葡糖胺残基和 N-乙酰基-β-D-葡糖胺低聚物的亲和性。WGA 不含蛋白结合糖。
具有四个结合位点的小麦凝集素对N-乙酰基-d-葡糖胺和N-乙酰基-d-神经氨酸(唾液酸)残基具有特异性。凝集素也起杀真菌剂的作用。它们还具有抗营养作用。

General description

来自 小麦 的凝集素是36kDa的二聚体糖蛋白。它属于几丁质结合蛋白家族。凝集素的糖基化前体在内质网中合成。

Other Notes

高度纯化

Preparation Note

由亲和纯化凝集素制备偶联物。

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

法规信息

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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Super-multiplex vibrational imaging
Wei L, et al.
Nature, 544, 465-465 (2017)
Effects of wheat germ agglutinin on human gastrointestinal epithelium: insights from an experimental model of immune/epithelial cell interaction
Dalla P, et al.
Toxicology and Applied Pharmacology, 237, 146-153 (2009)
Nuclear localization of Tob is important for regulation of its antiproliferative activity
Kawamura-Tsuzuku J, et al.
Oncogene, 23, 6630-6630 (2004)
Tsung-Lin Tsai et al.
International journal of nanomedicine, 7, 5215-5234 (2012-10-17)
Gold nanoparticles modified with the nuclear localization signal from simian virus 40 large T antigen (GNP-PEG/SV40) accumulate on the cytoplasmic side of the nuclear membrane in HeLa cells. Accumulation of GNP-PEG/SV40 around the nucleus blocks nucleocytoplasmic transport and prevents RNA
Pengfei Zhang et al.
Chemical science, 13(43), 12760-12768 (2022-12-16)
Exosome analysis is a promising tool for clinical and biological research applications. However, detection and biomarker quantification of exosomes is technically challenging because they are small and highly heterogeneous. Here, we report an optical approach for imaging exosomes and quantifying

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