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Merck
CN

L1045

LY-354740 水合物

≥98% (HPLC)

别名:

(1S,2S,5R,6S)-2-Aminobicyclo[3.1.0]hexane-2,6-dicarboxy lic acid, Eglumegad, Eglumetad, LY-354740

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关于此项目

经验公式(希尔记法):
C8H11NO4 · xH2O
分子量:
185.18 (anhydrous basis)
UNSPSC Code:
12352209
NACRES:
NA.77
eCl@ss:
32160406
Assay:
≥98% (HPLC)
Form:
solid
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Quality Segment

assay

≥98% (HPLC)

form

solid

solubility

deionized water: 8 mg/mL

originator

Eli Lilly

storage temp.

room temp

Application

LY-354740 hydrate has been used as a metabotropic glutamate receptor group II/III agonist to study its behavioral effectsof electric shock on Gammarus fossarum.

Biochem/physiol Actions

LY-354740 is a highly selective and potent agonist of group II mGlu (metabotropic glutamate) receptors.
LY-354740 is a highly selective and potent agonist of group II mGlu (metabotropic glutamate) receptors. It displays antianxiety and antiaddictive activity in vivo. It?s orally and systemically active. It is anxiolytic and inhibits symptoms of morphine withdrawal in morphine-dependent mice.

Features and Benefits

This compound is a featured product for Neuroscience research. Click here to discover more featured Neuroscience products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.
This compound is featured on the Glutamate Receptors (G Protein Family) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
This compound was developed by Eli Lilly. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.


象形图

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警示词

Warning

危险代码

Hazard Classifications

Acute Tox. 4 Oral

存储类别

11 - Combustible Solids

怎么回事?

WGK 3

闪点 (F)

Not applicable

闪点 (°C)

Not applicable



历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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