L121
Levallorphan tartrate salt
≥98% (HPLC), powder
别名:
17-(2-Propenyl)morphinan-3-ol tartrate
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经验公式（希尔记法）:
C19H25NO · C4H6O6
化学文摘社编号:
分子量:
433.49
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352200
EC Number:
200-767-3
MDL number:
InChI key
FWMLYVACGDQRFU-ZTMWJVNESA-N
InChI
1S/C19H25NO.C4H6O6/c1-2-10-20-11-9-19-8-4-3-5-16(19)18(20)12-14-6-7-15(21)13-17(14)19;5-1(3(7)8)2(6)4(9)10/h2,6-7,13,16,18,21H,1,3-5,8-12H2;1-2,5-6H,(H,7,8)(H,9,10)/t16-,18+,19+;1-,2-/m01/s1
SMILES string
O[C@H]([C@@H](O)C(O)=O)C(O)=O.[H][C@@]12CCCC[C@@]13CCN(CC=C)[C@@H]2Cc4ccc(O)cc34
assay
≥98% (HPLC)
form
powder
optical activity
[α]22/D −35°, c = 0.38 in H2O(lit.)
color
white to beige
solubility
H2O: 5 mg/mL, clear
originator
Roche
Quality Level
Gene Information
human ... OPRD1(4985), OPRM1(4988)
Biochem/physiol Actions
Partial agonist (antagonist) at μ and δ opioid receptors.
Features and Benefits
This compound was developed by Roche. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.
Disclaimer
Photosensitive
signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Oral
存储类别
11 - Combustible Solids
wgk
WGK 3
ppe
dust mask type N95 (US), Eyeshields, Gloves
法规信息
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D E Selley et al.
Molecular pharmacology, 51(1), 87-96 (1997-01-01)
G protein activation by different mu-selective opioid agonists was examined in rat thalamus, SK-N-SH cells, and mu-opioid receptor-transfected mMOR-CHO cells using agonist-stimulated guanosine-5'-O-(gamma-thio)-triphosphate ([35S]GTP gamma S) binding to membranes in the presence of excess GDP. [D-Ala2, N-MePhe4, Gly5-ol]Enkephalin (DAMGO) was
O V Bondar et al.
Acta naturae, 4(1), 78-81 (2012-06-19)
The dynamic light scattering (DLS) technique was applied in order to assess the zeta potential of the plasma membrane of human cells. At pH 7.4, the cell zeta potential for different types of cells showed variations over a wide range
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Quercetin (Que) is known to have biological benefits including an anticancer effect, but low water solubility limits its clinical application. The aim of this study was to develop a lecithin-based mixed polymeric micelle (LMPM) delivery system to improve the solubility
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