L121
Levallorphan tartrate salt
≥98% (HPLC), powder
别名:
17-(2-Propenyl)morphinan-3-ol tartrate
登录查看公司和协议定价
选择尺寸
关于此项目
经验公式（希尔记法）:
C19H25NO · C4H6O6
化学文摘社编号:
分子量:
433.49
EC 号:
MDL编号:
UNSPSC代码:
12352200
PubChem化学物质编号:
NACRES:
NA.77
质量水平
方案
≥98% (HPLC)
表单
powder
旋光性
[α]22/D −35°, c = 0.38 in H2O(lit.)
颜色
white to beige
溶解性
H2O: 5 mg/mL, clear
创始人
Roche
SMILES字符串
O[C@H]([C@@H](O)C(O)=O)C(O)=O.[H][C@@]12CCCC[C@@]13CCN(CC=C)[C@@H]2Cc4ccc(O)cc34
InChI
1S/C19H25NO.C4H6O6/c1-2-10-20-11-9-19-8-4-3-5-16(19)18(20)12-14-6-7-15(21)13-17(14)19;5-1(3(7)8)2(6)4(9)10/h2,6-7,13,16,18,21H,1,3-5,8-12H2;1-2,5-6H,(H,7,8)(H,9,10)/t16-,18+,19+;1-,2-/m01/s1
InChI key
FWMLYVACGDQRFU-ZTMWJVNESA-N
基因信息
human ... OPRD1(4985), OPRM1(4988)
生化/生理作用
Partial agonist (antagonist) at μ and δ opioid receptors.
特点和优势
This compound was developed by Roche. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.
免责声明
Photosensitive
警示用语：
Warning
危险声明
危险分类
Acute Tox. 4 Oral
储存分类代码
11 - Combustible Solids
WGK
WGK 3
个人防护装备
dust mask type N95 (US), Eyeshields, Gloves
法规信息
新产品
此项目有
D E Selley et al.
Molecular pharmacology, 51(1), 87-96 (1997-01-01)
G protein activation by different mu-selective opioid agonists was examined in rat thalamus, SK-N-SH cells, and mu-opioid receptor-transfected mMOR-CHO cells using agonist-stimulated guanosine-5'-O-(gamma-thio)-triphosphate ([35S]GTP gamma S) binding to membranes in the presence of excess GDP. [D-Ala2, N-MePhe4, Gly5-ol]Enkephalin (DAMGO) was
Ying-Chen Chen et al.
International journal of nanomedicine, 10, 7265-7274 (2015-12-15)
To alleviate the inherent problems of amphotericin B (AmB), such as poor water solubility and nephrotoxicity, a novel self-assembling mixed polymeric micelle delivery system based on lecithin and combined with amphiphilic polymers, Pluronic(®), Kolliphor(®), d-alpha tocopheryl polyethylene glycol succinate, and
Tzu-Pin Li et al.
Scientific reports, 7(1), 10674-10674 (2017-09-08)
This study involved physical and pharmacokinetic characterizations of trans-resveratrol (t-Rev)-loaded saLMPMs which attempted to improve t-Rev's pharmacokinetic profiles and bioavailability resolving hurdles limiting its potential health benefits. The optimal formulation consisted of t-Rev, lecithin, and Pluronic
Ghada A Abdelbary et al.
Drug delivery, 24(1), 309-319 (2017-02-07)
Vesicular drug carriers for ocular delivery have gained a real potential. Proniosomal gels as ocular drug carriers have been proven to be an effective way to improve bioavailability and patient compliance. Formulation and in vitro/ex vivo/in vivo characterization of ketoconazole
Ling-Chun Chen et al.
International journal of nanomedicine, 11, 1557-1566 (2016-05-05)
Quercetin (Que) is known to have biological benefits including an anticancer effect, but low water solubility limits its clinical application. The aim of this study was to develop a lecithin-based mixed polymeric micelle (LMPM) delivery system to improve the solubility
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系客户支持