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线性分子式:
CH3(CH2)4CH=CHCH2CH=CH(CH2)7CO2H
化学文摘社编号:
分子量:
280.45
UNSPSC Code:
12352211
NACRES:
NA.25
PubChem Substance ID:
EC Number:
200-470-9
Beilstein/REAXYS Number:
1727101
MDL number:
产品名称
亚油酸, ≥98%
InChI
1S/C18H32O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18(19)20/h6-7,9-10H,2-5,8,11-17H2,1H3,(H,19,20)/b7-6-,10-9-
InChI key
OYHQOLUKZRVURQ-HZJYTTRNSA-N
SMILES string
OC(CCCCCCC/C=C\C/C=C\CCCCC)=O
biological source
plant oil (safflower)
assay
≥98%
form
liquid
Quality Level
Gene Information
human ... SOAT1(6646), SOAT2(8435)
color
colorless
refractive index
n20/D 1.466
bp
229-230 °C/16 mmHg
mp
−5 °C
application(s)
life science and biopharma
functional group
carboxylic acid
lipid type
omega FAs
shipped in
ambient
storage temp.
−20°C
Application
亚油酸已用作测量脂氧合酶活性的底物。它还用于制备亚油酸氢过氧化物样品,并研究柠檬酸盐稳定的CeO2的促氧化活性。
Biochem/physiol Actions
亚油酸是一种n-6多不饱和必需脂肪酸(PUFA),是花生四烯酸(AA)和多种前列腺素的前体。亚油酸可用于改善抗癌药物的给药和疗效,并用于癌症保护。亚油酸显著影响膜功能。这种脂肪酸是生物活性代谢产物类花生酸的前体,类花生酸调节肾肺功能、血管张力和炎症反应。慢性脂肪吸收不良的婴儿会出现亚油酸缺乏。这种脂肪酸水平不足会导致婴儿生长发育不良、鳞状皮炎和免疫反应受损。亚油酸可保持皮肤水分含量,因此可用于局部涂敷。’
在原代鸭肝细胞中,亚油酸可增加PPARα及其靶基因(如酰基辅酶A氧化酶)的细胞增殖和基因表达 。
General description
亚油酸是一种重要的膳食ω-6脂肪酸。它是细胞膜的结构成分。
存储类别
10 - Combustible liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
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实验方案
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