L1376
α-Linoleic acid
≥98%
别名:
α亚油酸
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关于此项目
线性分子式:
CH3(CH2)4CH=CHCH2CH=CH(CH2)7CO2H
化学文摘社编号:
分子量:
280.45
Ballschmiter 编号:
1727101
EC 号:
MDL编号:
UNSPSC代码:
12352211
PubChem化学物质编号:
NACRES:
NA.25
生物来源
plant oil (safflower)
质量水平
方案
≥98%
表单
liquid
颜色
colorless
折射率
n20/D 1.466
沸点
229-230 °C/16 mmHg
mp
−5 °C
应用
life science and biopharma
官能团
carboxylic acid
脂质类型
omega FAs
运输
ambient
储存温度
−20°C
SMILES字符串
OC(CCCCCCC/C=C\C/C=C\CCCCC)=O
InChI
1S/C18H32O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18(19)20/h6-7,9-10H,2-5,8,11-17H2,1H3,(H,19,20)/b7-6-,10-9-
InChI key
OYHQOLUKZRVURQ-HZJYTTRNSA-N
基因信息
human ... SOAT1(6646), SOAT2(8435)
一般描述
亚油酸是一种重要的膳食ω-6脂肪酸。它是细胞膜的结构成分。
应用
亚油酸已用作测量脂氧合酶活性的底物。它还用于制备亚油酸氢过氧化物样品,并研究柠檬酸盐稳定的CeO2的促氧化活性。
生化/生理作用
亚油酸是一种n-6多不饱和必需脂肪酸(PUFA),是花生四烯酸(AA)和多种前列腺素的前体。亚油酸可用于改善抗癌药物的给药和疗效,并用于癌症保护。亚油酸显著影响膜功能。这种脂肪酸是生物活性代谢产物类花生酸的前体,类花生酸调节肾肺功能、血管张力和炎症反应。慢性脂肪吸收不良的婴儿会出现亚油酸缺乏。这种脂肪酸水平不足会导致婴儿生长发育不良、鳞状皮炎和免疫反应受损。亚油酸可保持皮肤水分含量,因此可用于局部涂敷。’
Linoleic acid increases cell proliferation and gene expression of PPARα and its target genes such as acyl-CoA oxidase in primary duck hepatocytes citation.
储存分类代码
10 - Combustible liquids
WGK
WGK 1
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves
Introduction: the role of fats in human diet
Sanders, Thomas AB
Functional Dietary Lipids (2016)
Céline Robo et al.
Acta biomaterialia, 72, 362-370 (2018-03-22)
Poly(methyl methacrylate) (PMMA) is the most commonly used material for the treatment of osteoporosis-induced vertebral compression fractures. However, its high stiffness may introduce an increased risk of adjacent vertebral fractures post-surgery. One alternative in overcoming this concern is the use
Fatty acids: Omega-6 polyunsaturated
Benjamin Caballero
Encyclopedia of Human Nutrition, 232-238 (2013)
Inactivation of soybean lipoxygenase in soymilk by pulsed electric fields
Li YQ, et al.
Food Chemistry, 109(2) (2008)
Philong Ta et al.
Journal of bacteriology, 193(8), 1981-1990 (2011-02-22)
The mshA::Tn5 mutant of Mycobacterium smegmatis does not produce mycothiol (MSH) and was found to markedly overproduce both ergothioneine and an ~15-kDa protein determined to be organic hydroperoxide resistance protein (Ohr). An mshA(G32D) mutant lacking MSH overproduced ergothioneine but not
商品
Importance and uses of linoleic acid in serum-free eukaryotic, including hybridoma and Chinese Hamster Ovary (CHO) cell, cultures
实验方案
Lipoprotein lipase (LPL) hydrolyzes triglycerides associated with VLDL.
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