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Merck
CN

L1882

来自 普通小麦 的凝集素（小麦）

agarose conjugate, saline suspension

别名:

Wheat germ agglutinin, WGA

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NACRES:
NA.32
UNSPSC Code:
12352202

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产品名称

来自 普通小麦 的凝集素（小麦）, agarose conjugate, saline suspension

Quality Level

200

conjugate

agarose conjugate

form

saline suspension

extent of labeling

5-10 mg per mL

matrix

cross-linked 4% beaded agarose

matrix activation

cyanogen bromide

capacity

≥0.1 mg/mL binding capacity (ovomucoid)

storage temp.

2-8°C

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相关类别

Biochem/physiol Actions

WGA 不具有血型特异性，但具有与 N-乙酰基-β-D-葡糖胺残基和 N-乙酰基-β-D-葡糖胺低聚物的亲和性。WGA 不含蛋白结合糖。
凝集素可用于鉴定、成像和靶向糖缀合物。与寡糖、糖蛋白和糖脂发生特异性相互作用。因此，凝集素用于微阵列测定，可实现有效的糖组谱分析。在植物和真菌内部，凝集素可抵御病原体或寄生物（feeder）侵袭。还参与宿主识别和组织粘附。

Application

用于纯化含有（D-N-乙酰氨基葡萄糖）2或N-乙酰神经氨酸的糖蛋白。

General description

凝集素是糖类结合蛋白，广泛存在于真菌、植物和动物中。凝集素的二级结构富含 β-链，表面具有糖类结合位点。

Physical form

悬浮于含15 mM叠氮化钠的1.0 M NaCl溶液中

Preparation Note

由亲和纯化凝集素制备偶联物。

存储类别

10 - Combustible liquids

wgk

WGK 3

ppe

Eyeshields, Gloves

法规信息

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分析证书(COA)

Lot/Batch Number
0000367703
0000315666
0000315653
0000315666
0000268585

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K Paz et al.
The Journal of biological chemistry, 271(12), 6998-7003 (1996-03-22)
A structural analysis has been carried out to determine which part of the intracellular domain of the insulin receptor (IR) beta subunit is involved in direct interaction with the receptor substrates IRS-1 and Shc. Toward this end, the juxtamembrane (JM)
Binding sugars: from natural lectins to synthetic receptors and engineered neolectins
Arnaud J, et al.
Chemical Society Reviews, 42(11), 4798-4813 (2013)
Shohei Wakao et al.
Cellular and molecular life sciences : CMLS, 79(11), 542-542 (2022-10-07)
Stem cells undergo cytokine-driven differentiation, but this process often takes longer than several weeks to complete. A novel mechanism for somatic stem cell differentiation via phagocytosing 'model cells' (apoptotic differentiated cells) was found to require only a short time frame.

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