产品名称
乳过氧化物酶 来源于牛奶, lyophilized powder (essentially salt-free), ≥200 units/mg protein
SMILES string
[O+H2]O[O-]
InChI key
JSPLKZUTYZBBKA-UHFFFAOYSA-N
InChI
1S/H2O3/c1-3-2/h1-2H
biological source
bovine milk
form
lyophilized powder (essentially salt-free)
specific activity
≥200 units/mg protein
absorbance ratio
A412/280 nm 0.7-0.9
UniProt accession no.
storage temp.
−20°C
Gene Information
cow ... LPO(280844)
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Analysis Note
Lowry法测蛋白。
Application
牛奶中的过氧化物酶用作牛奶过氧化物酶标准品,研究在原料乳中存在乳过氧化物酶时H2O2对抑制金黄色葡萄球菌生长的作用。它也用于乳过氧化物酶介导的碘化,以制备放射性标记肽。
Biochem/physiol Actions
乳过氧化物酶催化过氧化氢与碘化物的氧化反应生成碘。该活性提供了一种温和的特异性氯胺 T 替代物,用于蛋白质和 DNA 的放射性碘化反应。
乳过氧化物酶通过灭活多种微生物来促进牛奶的抗菌系统。这种乳过氧化物酶介导的抗菌系统也见于人类分泌物,如泪液、唾液和乳汁。乳过氧化物酶通过释放H2O2催化分子氧化。产物具有抗菌活性。
General description
乳过氧化物酶是存在于牛奶中的主要酶,属于过氧化物酶家族。它同时存在于植物和动物中。其酶结构包含由612个氨基酸残基组成的多肽链。
Other Notes
在25℃、pH 5.5条件下,一个单位可氧化1.0 μmM 2,2′-联氮基-双(3-乙基苯并噻唑啉-6-磺酸)。
signalword
Danger
hcodes
pcodes
Hazard Classifications
Resp. Sens. 1
存储类别
11 - Combustible Solids
wgk
WGK 1
ppe
Eyeshields, Gloves, type N95 (US)
法规信息
低风险生物材料
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