L2270
Lys-Ala 4-methoxy-β-naphthylamide dihydrochloride
dipeptidylpeptidase II substrate
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关于此项目
经验公式（希尔记法）:
C20H28N4O3 · 2HCl
化学文摘社编号:
分子量:
445.38
NACRES:
NA.28
PubChem Substance ID:
UNSPSC Code:
12352204
MDL number:
InChI
1S/C20H28N4O3.2ClH/c1-13(23-20(26)17(22)9-5-6-10-21)19(25)24-15-11-14-7-3-4-8-16(14)18(12-15)27-2;;/h3-4,7-8,11-13,17H,5-6,9-10,21-22H2,1-2H3,(H,23,26)(H,24,25);2*1H/t13-,17-;;/m0../s1
SMILES string
Cl.Cl.COc1cc(NC(=O)[C@H](C)NC(=O)[C@@H](N)CCCCN)cc2ccccc12
InChI key
GJOOJLYXFGXARX-ZMQOMOPGSA-N
assay
≥97.5% (TLC)
form
powder
solubility
water: 50 mg/mL, clear, colorless to yellow (and colorless to faint brown and colorless to brown-yellow)
storage temp.
−20°C
Quality Level
General description
Fluorogenic substrate for dipeptidyl aminopeptidase II.
Application
Lys-Ala 4-methoxy-β-naphthylamide dihydrochloride has been used as a substrate to measure the dipeptidyl peptidase II (DPPII) from Vigna radiata seeds.
signalword
Warning
hcodes
Hazard Classifications
Carc. 2
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
法规信息
新产品
此项目有
R Gossrau et al.
Histochemistry, 70(1), 53-76 (1980-01-01)
The activity of dipeptidylpeptidase II (DPP II; E.C. 3.4.14.2) was investigated by biochemical and histochemical methods in rat, mouse and guinea-pig organs as well as in human enterobiopsies. Lys-Pro-MNA and Ala-Pro-MNA showed the most favorable kinetic properties (Km, Vmax) and
F A Dolbeare et al.
Clinical chemistry, 23(8), 1485-1491 (1977-08-01)
Enzyme activity can be measured in single cells or in cell suspensions by either static or flow microfluorometry when a fluorogenic substrate is used. We have used amino acid derivatives of arylamines as fluorogenic substrates for tagging cellular proteinases. The
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