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L2378

γ-亚麻酸

Name: γ-亚麻酸
Brand: SIGMA

≥99%, liquid

别名:

γ-亚麻酸, 顺,顺,顺-6,9,12-十八碳三烯酸

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关于此项目

经验公式（希尔记法）:

C₁₈H₃₀O₂

化学文摘社编号:

506-26-3

分子量:

278.43

UNSPSC Code:

12352211

NACRES:

NA.25

PubChem Substance ID:

24896312

MDL number:

MFCD00065718

Beilstein/REAXYS Number:

1712253

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属性

biological source

plant oil (borage)

Quality Level

100

assay

≥99%

form

liquid

functional group

carboxylic acid

lipid type

omega FAs

shipped in

ambient

storage temp.

−20°C

SMILES string

CCCCC\C=C/C\C=C/C\C=C/CCCCC(O)=O

InChI

1S/C18H30O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18(19)20/h6-7,9-10,12-13H,2-5,8,11,14-17H2,1H3,(H,19,20)/b7-6-,10-9-,13-12-

InChI key

VZCCETWTMQHEPK-QNEBEIHSSA-N

说明

Application

γ-亚麻酸已被用作气相色谱法的分析标准品。可用于有关体重增加的营养研究和可能的肿瘤抑制药物。γ-亚麻酸用于研究不饱和脂肪酸的氧化/过氧化机制和预防。

Biochem/physiol Actions

γ-亚麻酸，一种多不饱和脂肪酸，通过降低人肠细胞样细胞系 Caco-2 和人中白细胞介素 (IL) 6 和 IL-8 的以及人体外树突状细胞产量发挥抗炎效果。

γ-亚麻酸盐 (C18:6,9,12) 与 α -亚麻酸 (C18:9,12,15) 在双键不同的位置。

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pictograms

GHS07

signalword

Warning

hcodes

H315,H319,H335

pcodes

P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

存储类别

10 - Combustible liquids

wgk

WGK 3

flash_point_f

230.0 °F - closed cup

flash_point_c

110 °C - closed cup

ppe

Eyeshields, Gloves, type ABEK (EN14387) respirator filter

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Evidence of the formation of different hydroperoxides in irradiated gamma-linolenate solutions: effect of micelle formation.

J Hindo et al.

Radiation research, 153(2), 201-207 (2000-01-12)

Peroxidation of unconjugated polyunsaturated fatty acids such as linolenic acid proceeds through a free radical chain mechanism and is accompanied by the formation of conjugated dienes such as hydroperoxides. In an investigation of radiation-induced oxidation of aqueous linolenate, we have

Nutritional and medical importance of gamma-linolenic acid.

D F Horrobin

Progress in lipid research, 31(2), 163-194 (1992-01-01)

Gamma-linolenic acid, arachidonic acid, and eicosapentaenoic acid as potential anticancer drugs.

U N Das

Nutrition (Burbank, Los Angeles County, Calif.), 6(6), 429-434 (1990-11-01)

Several in vitro studies and limited in vivo investigations showed that some cis-unsaturated fatty acids (c-UFAs) such as gamma-linolenic acid, arachidonic acid, and eicosapentaenoic acid have selective tumoricidal actions. This cytotoxic action of c-UFAs is produced by augmentation of free-radical

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全球贸易项目编号

货号	GTIN
L2378-500MG	04061833950012
L2378-10MG	04061833949993
L2378-100MG	04061833949986
L2378-1G	04061833950005