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经验公式(希尔记法):
C12H22O12
化学文摘社编号:
分子量:
358.30
UNSPSC Code:
12352201
NACRES:
NA.25
PubChem Substance ID:
EC Number:
202-538-3
Beilstein/REAXYS Number:
95054
MDL number:
产品名称
乳糖酸, ≥97% (TLC), cell impermeant agent
InChI key
JYTUSYBCFIZPBE-AMTLMPIISA-N
InChI
1S/C12H22O12/c13-1-3(15)10(7(18)8(19)11(21)22)24-12-9(20)6(17)5(16)4(2-14)23-12/h3-10,12-20H,1-2H2,(H,21,22)/t3-,4-,5+,6+,7-,8-,9-,10-,12+/m1/s1
SMILES string
OC[C@@H](O)[C@@H](O[C@@H]1O[C@H](CO)[C@H](O)[C@H](O)[C@H]1O)[C@H](O)[C@@H](O)C(O)=O
biological source
synthetic (organic
Organic)
assay
≥97% (TLC)
form
powder
color
white
mp
113-118 °C (lit.)
solubility
water: 50 mg/mL, clear, colorless
storage temp.
room temp
Quality Level
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Application
乳糖酸可用作对照品,用于运动发酵单胞菌产生的乳糖酸的化学表征。
用于器官保存的细胞渗透剂
Biochem/physiol Actions
乳糖酸具有抗氧化剂和稳定剂-胶凝剂的作用。它可用作食品和药品中的成分。
据报道可抑制羟基自由基的产生。基质金属蛋白酶(MMP)的隐性抑制剂(cryptic inhibitor)。可耐受饮食代谢,但可刺激大鼠肠道内钙的吸收。
General description
乳糖酸是乳糖的衍生物,它是一种由葡萄糖酸和半乳糖制备的醛糖酸。它是一种潜在的螯合剂、防腐剂和益生元(prebiotic)。
存储类别
11 - Combustible Solids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
法规信息
涉药品监管产品
此项目有
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R Brommage et al.
The Journal of nutrition, 123(12), 2186-2194 (1993-12-01)
Lactulose is a disaccharide analogue of lactose that is resistant to metabolism in the small intestine but not in the large intestine. The effects of lactulose and other sugars on intestinal Ca absorption were determined from the decrease in the
J H Southard et al.
Annual review of medicine, 46, 235-247 (1995-01-01)
Organ preservation is the supply line for organ transplantation. Currently, the liver, pancreas, and kidney can be successfully preserved for up to two days by flushing the organs with the University of Wisconsin (UW) organ preservation solution and storing them
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Valle TA, et al.
Pharmaceutica Analytica Acta, 4, 1-5 (2013)
Lactobionic acid: a high value-added lactose derivative for food and pharmaceutical applications
International dairy journal, 26(2), 103-111 (2012)
J A Wahlberg et al.
Transplantation, 43(1), 5-8 (1987-01-01)
A new flushout solution for preservation of the pancreas was tested in the dog model of segmental pancreas autotransplantation. The solution osmolality was 320 mOsm/L, K+ = 120 mM, Na+ = 30 mM, and it contained the anion, lactobionate, and
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