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Merck
CN

L2885

Lymphotoxin-β Receptor/Fc Chimera human

>95% (SDS-PAGE), recombinant, expressed in NSO cells, lyophilized powder, suitable for cell culture

别名:

TNF R-related protein, TNF RIII

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关于此项目

UNSPSC Code:
51111800
MDL number:
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biological source

human

recombinant

expressed in NSO cells

assay

>95% (SDS-PAGE)

form

lyophilized powder

mol wt

monomer calculated mol wt 49.6 kDa, 70 kDa by SDS-PAGE (reducing) (due to glycosylation)

packaging

pkg of 100 μg

storage condition

avoid repeated freeze/thaw cycles

technique(s)

cell culture | mammalian: suitable

impurities

endotoxin, tested

UniProt accession no.

storage temp.

−20°C

Gene Information

human ... LTBR(4055)

Biochem/physiol Actions

LTBR (lymphotoxin β receptor) is a receptor for LIGHT (tumor necrosis factor ligand superfamily member 14) and LT (lymphotoxin)-a1β2. It is present in the epithelial, stromal and myeloid cells. LTBR participates in lymphoid organ development and immune homeostasis. It is also involved in the lipopolysaccharide (LPS)-mediated expression of IL (interleukin)-8.

Physical form

Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline.

Analysis Note

The biological activity is measured by the ability of the immobilized LTβR/Fc to bind LTα2/β1 and LTα1/β2 in a functional ELISA.

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

法规信息

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分析证书(COA)

Lot/Batch Number

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Seok-Won Jang et al.
Immunology letters, 165(2), 63-69 (2015-04-19)
Lymphotoxin-beta receptor (LTβR), a receptor for LIGHT and LTα1β2, is expressed on the epithelial, stromal, and myeloid cells. LTβR is known to affect the lymphoid organ development and immune homeostasis. However, its role in macrophage function has not been sufficiently
M Baens et al.
Genomics, 16(1), 214-218 (1993-04-01)
An arrayed library of human heterogeneous nuclear complementary (hnc) DNA was constructed from a somatic cell hybrid (M28) containing an i(12p) marker as the sole human chromosome. Heterogeneous nuclear (hn) RNA of M28 was used to synthesize first-strand hncDNA with

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