L3265
脂磷壁酸 来源于枯草芽孢杆菌
生化/生理作用
脂磷壁酸 (LTA) 是一种连接在革兰氏阳性菌细胞壁上富含脂质的磷壁酸。LTA 是一种病原体相关分子模式 (PAMP) ，被 Toll 样受体 2 (TLR2) 识别，这种识别导致 NF-kB 的激活。
脂磷壁酸 (LTA) 是革兰氏阳性菌细胞壁的一种复杂成分，参与广泛的细胞过程，如刺激免疫应答和细胞信号通路。LTA 在革兰氏阳性菌物种之间存在差异。 枯草芽孢杆菌 产生的脂磷壁酸可用于比较其结构、免疫原性和与其他细菌 LTA 的功能。
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
Mardi A Crane-Godreau et al.
Infection and immunity, 73(1), 476-484 (2004-12-25)
Having previously shown that CCL20/macrophage inflammatory protein 3alpha and tumor necrosis factor alpha (TNF-alpha) are released by polarized primary rat uterine epithelial cells (UEC) in response to Escherichia coli but not to Lactobacillus rhamnosus, we sought to determine if epithelial
Xiang-Jun Rao et al.
Developmental and comparative immunology, 34(10), 1119-1128 (2010-07-06)
Activation of prophenoloxidase and synthesis of antimicrobial peptides (AMPs) are two important innate immune mechanisms in insects. In the current study, we investigated immune responses activated by three major bacterial components, lipopolysaccharide (LPS) (including rough mutants of LPS), lipoteichoic acid
Siegfried Morath et al.
Journal of endotoxin research, 11(6), 348-356 (2005-11-24)
The role of lipoteichoic acids (LTAs) from Gram-positive bacteria as immunostimulatory molecules was controversial for many years, as inadequate preparation methods as well as heterogeneous and endotoxin-contaminated commercial preparations led to conflicting results. An improved purification methodology for LTA now
Bing Yang et al.
PloS one, 8(5), e64106-e64106 (2013-05-30)
Insect prophenoloxidase (PPO) is essential for physiological functions such as melanization of invading pathogens, wound healing and cuticle sclerotization. The insect PPO activation pathway is well understood. However, it is not very clear how PPO is released from hemocytes and
Intrinsic nitric oxide-stimulatory activity of lipoteichoic acids from different Gram-positive bacteria.
Zidek Z, Farghali H, Kmonickova E.
Nitric Oxide, 232, 300-310 (2010)
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