L4897

Luteinizing hormone releasing hormone salmon

Name: Luteinizing hormone releasing hormone salmon
Brand: SIGMA

≥97% (HPLC)

别名:

GnRH, Gonadoliberin, Gonadotropin releasing hormone, LH-RH

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经验公式（希尔记法）:

C₆₀H₇₃N₁₅O₁₃

化学文摘社编号:

86073-88-3

分子量:

1212.31

NACRES:

NA.32

PubChem Substance ID:

24896381

UNSPSC Code:

51111800

MDL number:

MFCD00133497

主要文件

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产品名称

Luteinizing hormone releasing hormone salmon, ≥97% (HPLC)

InChI

1S/C60H73N15O13/c1-32(2)20-47(60(88)75-19-7-12-49(75)59(87)65-28-50(61)78)73-55(83)44(22-34-25-63-40-10-5-3-8-38(34)40)69-52(80)29-66-53(81)43(21-33-13-15-37(77)16-14-33)70-58(86)48(30-76)74-56(84)45(23-35-26-64-41-11-6-4-9-39(35)41)71-57(85)46(24-36-27-62-31-67-36)72-54(82)42-17-18-51(79)68-42/h3-6,8-11,13-16,25-27,31-32,42-49,63-64,76-77H,7,12,17-24,28-30H2,1-2H3,(H2,61,78)(H,62,67)(H,65,87)(H,66,81)(H,68,79)(H,69,80)(H,70,86)(H,71,85)(H,72,82)(H,73,83)(H,74,84)

SMILES string

CC(C)CC(NC(=O)C(Cc1c[nH]c2ccccc12)NC(=O)CNC(=O)C(Cc3ccc(O)cc3)NC(=O)C(CO)NC(=O)C(Cc4c[nH]c5ccccc45)NC(=O)C(Cc6cnc[nH]6)NC(=O)C7CCC(=O)N7)C(=O)N8CCCC8C(=O)NCC(N)=O

InChI key

NMJREATYWWNIKX-UHFFFAOYSA-N

assay

≥97% (HPLC)

UniProt accession no.

P55248
P01148
P07490
P13562
P30968
P30969
Q01776

storage temp.

−20°C

Quality Level

200

Gene Information

human ... GNRH1(2796), GNRHR(2798)
mouse ... GNRH1(14714), GNRHR(14715)
rat ... GNRH1(25194), GNRHR(81668)

Application

Luteinizing hormone releasing hormone (salmon) has been used to study the effect of LHRH (luteinizing hormone releasing hormone) in the brain of Podarcis sicula sicula (male) during reproduction. It has been used to study the hormonal regulation of PACAP (pituitary adenylate cyclase-activating polypeptide) and its receptor, PAC1 (adenylate cyclase activating polypeptide 1 (pituitary) receptor type I).

Biochem/physiol Actions

Hypothalamic peptide that stimulates release of gonadotrophins from anterior pituitary, thus regulating reproductive functions.

Stimulates release of gonadotrophins from anterior pituitary.

Other Notes

Lyophilized from 0.5% acetic acid

pictograms

GHS08

signalword

Danger

hcodes

H360

pcodes

P201 - P308 + P313

Hazard Classifications

Repr. 1B

存储类别

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type P3 (EN 143) respirator cartridges

法规信息

新产品

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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

0000428464

0000321059

0000224316

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Relationships among GnRH, substance P, prostaglandins, sex steroids and aromatase activity in the brain of the male lizard Podarcis sicula sicula during reproduction.

A Gobbetti et al.

Journal of reproduction and fertility, 101(3), 523-529 (1994-08-01)

The release of PGF2 alpha and PGE2, progesterone, androgens and oestradiol in vitro, and the aromatase activity in the brain of the male lizard Podarcis sicula sicula during three different phases of the reproductive period were evaluated. In addition, the

Interaction of gonadal steroids and gonadotropin-releasing hormone on pituitary adenylate cyclase-activating polypeptide (PACAP) and PACAP receptor expression in cultured rat anterior pituitary cells.

Weiming Zheng et al.

Reproductive sciences (Thousand Oaks, Calif.), 21(1), 41-51 (2013-05-22)

Pituitary adenylate cyclase-activating polypeptide (PACAP) and its receptors are expressed in the hypothalamus, the gonadotrope cells of the anterior pituitary gland, and the gonads, forming an autocrine-paracrine system in these tissues. Within the pituitary, PACAP functions either alone or synergistically

Vasoactive Intestinal Peptide Indirectly Elicits Pituitary LH Secretion Independent of GnRH in Female Zebrafish.

Tanaka, et al.

Endocrinology, 163 (2022)

Parenteral administration of GnRH constructs and adjuvants: immune responses and effects on reproductive tissues of male mice.

Sameer Sharma et al.

Vaccine, 32(43), 5555-5563 (2014-08-19)

Two gonadotrophin releasing hormone (GnRH) constructs prepared by either chemical conjugation to keyhole limpet hemocyanin (GnRH-KLH) or as an expressed recombinant fusion protein (Multimer) were evaluated with or without adjuvants (immunostimulating complexes, ISCOMs, or cytosine-phosphate-guanosine oligodeoxynucleotides, CpG ODNs). After subcutaneous

Kisspeptin-gpr54 signaling at the GnRH neuron is necessary for negative feedback regulation of luteinizing hormone secretion in female mice.

Shel-Hwa Yeo et al.

Neuroendocrinology, 100(2-3), 191-197 (2014-10-11)

Kisspeptin-Gpr54 signaling is critical for regulating the activity of gonadotropin-releasing hormone (GnRH) neurons in mammals. Previous studies have shown that the negative feedback mechanism is disrupted in global Gpr54-null mutants. The present investigation aimed to determine (1) if a lack

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Luteinizing hormone releasing hormone salmon

≥97% (HPLC)

选择尺寸

关于此项目

主要文件

属性

产品名称

InChI

SMILES string

InChI key

assay

UniProt accession no.

storage temp.

Quality Level

Gene Information

说明

Application

Biochem/physiol Actions

Other Notes

安全信息

pictograms

signalword

hcodes

pcodes

Hazard Classifications

存储类别

wgk

flash_point_f

flash_point_c

ppe

法规信息

文件

分析证书(COA)

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