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Merck
CN

L5143

左啡诺 (+)-酒石酸盐 二水合物

white, powder, ≥98% (HPLC)

别名:

L-3-Hydroxy-N-methylmorphinan (+)-tartrate salt dihydrate

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关于此项目

经验公式（希尔记法）:
C17H23NO · C4H6O6 · 2H2O
化学文摘社编号:
5985-38-6
分子量:
443.49
UNSPSC Code:
12352200
NACRES:
NA.77
EC Number:
204-753-8
MDL number:
MFCD00151497

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SMILES string

N1([C@H]2[C@H]3[C@](CC1)(CCCC3)c4c(ccc(c4)O)C2)C.O[C@H]([C@@H](O)C(=O)O)C(=O)O.O.O

InChI key

UMZNDVASJKIQCB-QLFXFZCRSA-N

InChI

1S/C17H23NO.C4H6O6.2H2O/c1-18-9-8-17-7-3-2-4-14(17)16(18)10-12-5-6-13(19)11-15(12)17;5-1(3(7)8)2(6)4(9)10;;/h5-6,11,14,16,19H,2-4,7-10H2,1H3;1-2,5-6H,(H,7,8)(H,9,10);2*1H2/t14-,16+,17+;1-,2-;;/m01../s1

assay

≥98% (HPLC)

form

powder

drug control

USDEA Schedule II; Home Office Schedule 2; stupéfiant (France); kontrollierte Droge in Deutschland; regulated under CDSA - not available from Sigma-Aldrich Canada; estupefaciente (Spain); Decreto Lei 15/93: Tabela IA (Portugal), kontrollierte Droge in Deutschland

Quality Level

200

storage condition

protect from light

color

white

solubility

H2O: >20 mg/mL

相关类别

Biochem/physiol Actions

Synthetic morphine analog that is a narcotic analgesic and μ opioid receptor agonist.

Legal Information

German
Dieses Produkt fällt unter das Betäubungsmittelgesetz (BtMG). Für eine Bestellung dieses Produktes ist eine Erlaubnis nach § 3 BtMG zwingend erforderlich, es sei denn, es greift eine Ausnahme von der Erlaubnispflicht nach § 4 oder § 26 BtMG.

English
This product is subject to the German Narcotics Act. A permit under Section 3 of the German Narcotics Act is mandatory for ordering this product unless an exemption from the permit requirement under Section 4 or Section 26 of the German Narcotics Act applies.

pictograms

Skull and crossbonesHealth hazard
GHS06,GHS08

signalword

Danger

Hazard Classifications

Acute Tox. 3 Oral - Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Repr. 1B - Resp. Sens. 1 - Skin Sens. 1

存储类别

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges

法规信息

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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
SLCH9629
SLCB1163
SLBV0090
047K1431V
047K1431

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D Morgan et al.
The Journal of pharmacology and experimental therapeutics, 289(2), 965-975 (1999-04-24)
Effects of low (butorphanol, nalbuphine)-, intermediate (buprenorphine)-, and high (morphine, levorphanol)-efficacy mu opioids were examined in F344, Sprague-Dawley (SD), Long-Evans (LE), and Lewis rats using a tail withdrawal and a drug discrimination procedure. In the tail withdrawal procedure using low
J R Bunzow et al.
Journal of neurochemistry, 64(1), 14-24 (1995-01-01)
We have cloned and expressed a rat brain cDNA, TS11, that encodes a mu-opioid receptor based on pharmacological, physiological, and anatomical criteria. Membranes were prepared from COS-7 cells transiently expressing TS11 bound [3H]diprenorphine with high affinity (KD = 0.23 +/-

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