L5170
Leukotriene A4 Hydrolase human
recombinant, expressed in E. coli
别名:
LTA-4 hydrolase, LTA4, LTA4H
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关于此项目
化学文摘社编号:
UNSPSC Code:
12352204
NACRES:
NA.54
EC 号:
MDL number:
recombinant
expressed in E. coli
description
contains C-terminal his-tag
assay
≥90% (SDS-PAGE)
mol wt
~69 kDa
NCBI accession no.
shipped in
dry ice
storage temp.
−70°C
Gene Information
human ... LTA4H(4048)
Application
Biochem/physiol Actions
Leukotriene A4 Hydrolase human (LTA4H) is a bifunctional zinc metalloenzyme that converts LTA4 into Leukotriene B4, and also demonstrates aminopeptidase activity. Leukotriene B4 is a lipid chemoattractant that plays critical roles in inflammaton, immune responses, host defenses against infections, and lipid homeostasis. Inhibition of LTA4H in a mouse model decreases LTB4 in the airways and attenuates airway inflammation and airway hyperreactivity through modulation of T cell and dendritic cell function .
Physical form
Supplied as a solution in 100mM Tris, pH 8.0, containing 20% glycerol and 100mM potassium chloride.
存储类别
12 - Non Combustible Liquids
怎么回事？
WGK 1
闪点 (F)
Not applicable
闪点 (°C)
Not applicable