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关于此项目
经验公式(希尔记法):
C24H50NO7P
化学文摘社编号:
分子量:
495.63
UNSPSC Code:
51191904
NACRES:
NA.25
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
5385682
产品名称
1-棕榈酰-sn-甘油-3-磷酸胆碱, synthetic, ≥99%
InChI
1S/C24H50NO7P/c1-5-6-7-8-9-10-11-12-13-14-15-16-17-18-24(27)30-21-23(26)22-32-33(28,29)31-20-19-25(2,3)4/h23,26H,5-22H2,1-4H3/t23-/m1/s1
SMILES string
O[C@](COP([O-])(OCC[N+](C)(C)C)=O)([H])COC(CCCCCCCCCCCCCCC)=O
InChI key
ASWBNKHCZGQVJV-HSZRJFAPSA-N
biological source
synthetic
assay
≥99%
form
powder
functional group
phospholipid
lipid type
phosphoglycerides
shipped in
ambient
storage temp.
−20°C
Quality Level
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Biochem/physiol Actions
1-棕榈酰-sn-甘油-3-磷酸胆碱可用作底物以鉴定、区分和表征溶血磷酸胆碱转酰基转移酶。
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Akira Sato et al.
Chemical biology & drug design, 80(3), 417-425 (2012-05-18)
Lysophosphatidylcholine, a major phospholipid component of oxidized low-density lipoprotein, is implicated in many inflammatory diseases, including atherosclerosis. We previously reported that Asp-hemolysin-related synthetic peptide (P21) composed of 21 amino acid residues markedly inhibits the bioactivities of oxidized low-density lipoprotein and
Inna A Nikonorova et al.
Nucleic acids research, 42(20), 12779-12788 (2014-10-19)
TRPM7 is an essential and ubiquitous channel-kinase regulating cellular influx of Mg2+. Although TRPM7 mRNA is highly abundant, very small amount of the protein is detected in cells, suggesting post-transcriptional regulation of trpm7 gene expression. We found that TRPM7 mRNA
J Wang et al.
Circulation, 104(22), 2645-2648 (2001-11-28)
Lysophosphatidylcholine (LPC), a naturally occurring phospholipid metabolite, accumulates in the ischemic heart and causes extracellular K(+) accumulation and action potential shortening. LPC has been incriminated as a biochemical trigger of lethal cardiac arrhythmias, but the underlying mechanisms remain poorly understood.
Lu-Cheng Cao et al.
Kidney international, 66(5), 1890-1900 (2004-10-22)
In cultured renal epithelial cells, exposure to oxalate, a constituent of many kidney stones, elicits a cascade of responses that often leads to cell death. Oxalate toxicity is mediated via generation of reactive oxygen species (ROS) in a process that
Thomas Pulinilkunnil et al.
Cardiovascular research, 59(3), 788-797 (2003-09-23)
Lipoprotein lipase (LPL) mediated hydrolysis of circulating triglyceride (TG)-rich lipoproteins provides the heart with fatty acids. The present study was designed to investigate the influence of circulating TG and their lipolysis in facilitating translocation of LPL from the underlying cardiomyocyte
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