L5918
洛莫司汀
≥98%
别名:
1-(2-Chloroethyl)-3-cyclohexyl-1-nitrosourea
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关于此项目
经验公式（希尔记法）:
C9H16ClN3O2
化学文摘社编号:
分子量:
233.70
NACRES:
NA.25
PubChem Substance ID:
UNSPSC Code:
12352100
EC Number:
235-859-2
MDL number:
Biochem/physiol Actions
Antineoplastic agent with cellular DNA effects. Lomustine induces p53 expression in A2870 cells.
signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 3 Oral - Carc. 1B
存储类别
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
wgk
WGK 3
ppe
Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges
Tracy T Batchelor et al.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 31(26), 3212-3218 (2013-08-14)
A randomized, phase III, placebo-controlled, partially blinded clinical trial (REGAL [Recent in in Glioblastoma Alone and With Lomustine]) was conducted to determine the efficacy of cediranib, an oral pan-vascular endothelial growth factor (VEGF) receptor tyrosine kinase inhibitor, either as monotherapy
Daisuke Hasegawa et al.
The Journal of veterinary medical science, 74(11), 1517-1521 (2012-07-13)
A 9 year-old, neutered, male French Bulldog showing cluster seizures was diagnosed with a glioma in the right piriform cortex by MRI. Hypofractionated radiation therapy (RT) was performed using a linear accelerator. Although the lesion had involuted significantly at 2
Greg Yothers et al.
Journal of the National Cancer Institute, 103(20), 1498-1506 (2011-10-15)
Among patients with resected colon cancer, black patients have worse survival than whites. We investigated whether disparities in survival and related endpoints would persist when patients were treated with identical therapies in controlled clinical trials. We assessed 14,611 patients (1218
Thierry Gorlia et al.
European journal of cancer (Oxford, England : 1990), 49(16), 3477-3485 (2013-07-31)
The prognosis of patients with anaplastic oligodendrogliomas (AOD) and oligoastrocytomas (AOA) is variable. Biomarkers might be helpful to identify more homogeneous disease subtypes and improve therapeutic index. The aim of this study is to develop new clinical, pathological and molecular
Late and prolonged pseudoprogression in glioblastoma after treatment with lomustine and temozolomide.
Moritz Stuplich et al.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 30(21), e180-e183 (2012-06-13)
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